• Gene id: 257240

Gene Summary

• Gene Symbol: KLHL34   Gene   UCSC   Ensembl
• Gene name: kelch like family member 34
• Alternate names: kelch-like protein 34, RP11-450P7.3, kelch-like 34,
• Gene location: Xp22.12 (21658329: 21654689)     Exons: 1     NC_000023.11

Protein Summary

• Protein general information: Q8N239  
  • Name: Kelch like protein 34
  • Length: 644  
  • Mass: 70612
• Sequence:

  MSYFLSYCKAHGGALLTGYQALRAEGFLCDVTLETEGSEFPAHRSLLACSSDYFRALFKSHTQESRARVIHLHVP
  SAAGLQRLLDFIYTAWLSLSMDTVEDTLEAASYLQVTEALGLCGRYLERQLAPENCCFAANVAARFGLAHTLDAA
  ERCIVSHLQELLARGAGPAGLLELNPTSLRAVLGAPDVARVPEARLLGLALAWLRQEPTTERLAHCTELLERVRF
  GLVPADVLRRVYSGSGLVLPARVKGLIIQALNYHTTPSRQPLMQGEQTSIRSPQTRILLVGGRRAREVVIEEVAA
  PQRAARGQVAAPEPEEEEEELEEEEEEEEWELTQNVVAFDVYNHRWRSLTQLPTPLLGHSVCTAGNFLFVLGGES
  PSGSASSPLADDSRVVTAQVHRYDPRFHAWTEVPAMREARAHFWCGAVGERLLAVGGLGAGGEVLASVEMYDLRR
  DRWTAAGALPRALHGHAGAVGDRGVVYISGGKAGRGEGGASSLRDLYVLGPEEQVWSKKAPMGTARFGHHMAVLR
  GAVFAFLGRYEPFSEIERYDPGADQWTRLRPLPYDRFCYGLAVVEETALLLGGLKWRDSRQVPTRNVVGYDLDLD
  RWEDIGCALPWAWSGLRCAVLQLAEGGDDEREGEVGEALDLVLG

• Structural information:
  • Protein Domains: (29..9-)
    (/note="BTB-)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00037-)
    (131..23-)
    (/note="BACK"-)
  • Interpro: IPR011705  IPR017096  IPR000210  IPR015915  IPR006652   IPR011333  
  • Prosite: PS50097
  • STRING: ENSP00000368813
• Other Databases: GeneCards:  KLHL34  Malacards:  KLHL34

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005615	extracellular space	HDA	cellular component

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)