• Gene id: 256380

Gene Summary

• Gene Symbol: SCML4   Gene   UCSC   Ensembl
• Aliases: dJ47M23.1
• Gene name: Scm polycomb group protein like 4
• Alternate names: sex comb on midleg-like protein 4, sex comb on midleg like 4,
• Gene location: 6q21 (107845958: 107697296)     Exons: 17     NC_000006.12
• OMIM: 610133

Protein Summary

• Protein general information: Q8N228  
  • Name: Sex comb on midleg like protein 4
  • Length: 414  
  • Mass: 45023
• Sequence:

  MQSQRIPGRKRGRPSLHSTPMKMAVHNLYSASAGSLPAVKIPKKRGRKPGYKIKSRVLMTPLALSPPRSTPEPDL
  SSIPQDAATVPSLAAPQALTVCLYINKQANAGPYLERKKVQQLPEHFGPERPSAVLQQAVQACIDCAHQQKLVFS
  LVKQGYGGEMVSVSASFDGKQHLRSLPVVNSIGYVLRFLAKLCRSLLCDDLFSHQPFPRGCSASEKVQEKEEGRM
  ESVKTVTTEEYLVNPVGMNRYSVDTSASTFNHRGSLHPSSSLYCKRQNSGDSHLGGGPAATAGGPRTSPMSSGGP
  SAPGLRPPASSPKRNTTSLEGNRCASSPSQDAQDARRPRSRNPSAWTVEDVVWFVKDADPQALGPHVELFRKHEI
  DGNALLLLKSDMVMKYLGLKLGPALKLCYHIDKLKQAKF

• Structural information:
  • Protein Domains: (288..35-)
    (/note="SAM"-)
  • Interpro: IPR001660  IPR013761  IPR033763  IPR021987  IPR038348  
  • STRING: ENSP00000358016
• Other Databases: GeneCards:  SCML4  Malacards:  SCML4

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005634	nucleus	IBA	cellular component
GO:0003682	chromatin binding	IBA	molecular function
GO:0042393	histone binding	IBA	molecular function
GO:0045892	negative regulation of transcription, DNA-templated	IBA	biological process
GO:0005634	nucleus	IEA	cellular component
GO:0005634	nucleus	IEA	cellular component

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq