• Gene id: 256356

Gene Summary

• Gene Symbol: GK5   Gene   UCSC   Ensembl
• Gene name: glycerol kinase 5
• Alternate names: putative glycerol kinase 5, ATP:glycerol 3-phosphotransferase 5, GK 5, glycerokinase 5, glycerol kinase 5 (putative),
• Gene location: 3q23 (142225591: 142157526)     Exons: 19     NC_000003.12
• OMIM: 0

Protein Summary

• Protein general information: Q6ZS86  
  • Name: Putative glycerol kinase 5 (GK 5) (Glycerokinase 5) (EC 2.7.1.30) (ATP:glycerol 3 phosphotransferase 5)
  • Length: 529  
  • Mass: 59156
• Sequence:

  MSGLLTDPEQRAQEPRYPGFVLGLDVGSSVIRCHVYDRAARVCGSSVQKVENLYPQIGWVEIDPDVLWIQFVAVI
  KEAVKAAGIQMNQIVGLGISTQRATFITWNKKTGNHFHNFISWQDLRAVELVKSWNNSLLMKIFHSSCRVLHFFT
  RSKRLFTASLFTFTTQQTSLRLVWILQNLTEVQKAVEEENCCFGTIDTWLLYKLTKGSVYATDFSNASTTGLFDP
  YKMCWSGMITSLISIPLSLLPPVRDTSHNFGSVDEEIFGVPIPIVALVADQQSAMFGECCFQTGDVKLTMGTGTF
  LDINTGNSLQQTTGGFYPLIGWKIGQEVVCLAESNAGDTGTAIKWAQQLDLFTDAAETEKMAKSLEDSEGVCFVP
  SFSGLQAPLNDPWACASFMGLKPSTSKYHLVRAILESIAFRNKQLYEMMKKEIHIPVRKIRADGGVCKNGFVMQM
  TSDLINENIDRPADIDMSCLGAASLAGLAVGFWTDKEELKKLRQSEVVFKPQKKCQEYEMSLENWAKAVKRSMNW
  YNKT

• Structural information:
  • Interpro: IPR000577  IPR018485  IPR018483  IPR018484  IPR037444  
  • Prosite: PS00445
  • CDD: cd07793
  • STRING: ENSP00000418001
• Other Databases: GeneCards:  GK5  Malacards:  GK5

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0046167	glycerol-3-phosphate biosynthetic process	IBA	biological process
GO:0006071	glycerol metabolic process	IBA	biological process
GO:0004370	glycerol kinase activity	IBA	molecular function
GO:0016773	phosphotransferase activity, alcohol group as acceptor	IBA	molecular function
GO:0016310	phosphorylation	IBA	biological process
GO:0006641	triglyceride metabolic process	IBA	biological process
GO:0005739	mitochondrion	IBA	cellular component
GO:0005975	carbohydrate metabolic process	IEA	biological process
GO:0016773	phosphotransferase activity, alcohol group as acceptor	IEA	molecular function
GO:0006071	glycerol metabolic process	IEA	biological process
GO:0016301	kinase activity	IEA	molecular function
GO:0016740	transferase activity	IEA	molecular function
GO:0016310	phosphorylation	IEA	biological process
GO:0005524	ATP binding	IEA	molecular function
GO:0000166	nucleotide binding	IEA	molecular function
GO:0004370	glycerol kinase activity	IEA	molecular function
GO:0019563	glycerol catabolic process	IEA	biological process

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)