• Gene id: 256309

Gene Summary

• Gene Symbol: CCDC110   Gene   UCSC   Ensembl
• Aliases: CT52, KM-HN-1, KMHN1
• Gene name: coiled-coil domain containing 110
• Alternate names: coiled-coil domain-containing protein 110, cancer/testis antigen 52, cancer/testis antigen KM-HN-1,
• Gene location: 4q35.1 (185471751: 185445181)     Exons: 13     NC_000004.12
• OMIM: 609488

Protein Summary

• Protein general information: Q8TBZ0  
  • Name: Coiled coil domain containing protein 110 (Cancer/testis antigen 52) (CT52) (Cancer/testis antigen KM HN 1)
  • Length: 833  
  • Mass: 96726
  • Tissue specificity: Expressed specifically in testis. Also expressed in tumors of different origins. {ECO
• Sequence:

  MSPEKQHREEDEVDSVLLSASKILNSSEGVKESGCSDTEYGCIAESENQIQPQSALKVLQQQLESFQALRMQTLQ
  NVSMVQSEISEILNKSIIEVENPQFSSEKNLVFGTRIEKDLPTENQEENLSMEKSHHFEDSKTLHSVEEKLSGDS
  VNSLPQSVNVPSQIHSEDTLTLRTSTDNLSSNIIIHPSENSDILKNYNNFYRFLPTAPPNVMSQADTVILDKSKI
  TVPFLKHGFCENLDDICHSIKQMKEELQKSHDGEVALTNELQTLQTDPDVHRNGKYDMSPIHQDKMNFIKEENLD
  GNLNEDIKSKRISELEALVKKLLPFRETVSKFHVHFCRKCKKLSKSEMHRGKKNEKNNKEIPITGKNITDLKFHS
  RVPRYTLSFLDQTKHEMKDKERQPFLVKQGSIISENEKTSKVNSVTEQCVAKIQYLQNYLKESVQIQKKVMELES
  ENLNLKSKMKPLIFTTQSLIQKVETYEKQLKNLVEEKSTIQSKLSKTEEYSKECLKEFKKIISKYNVLQGQNKTL
  EEKNIQLSLEKQQMMEALDQLKSKEHKTQSDMAIVNNENNRMSIEMEAMKTNILLIQDEKEMLEKKTHQLLKEKS
  SLGNELKESQLEIIQLKEKERLAKTEQETLLQIIETVKDEKLNLETTLQESTAARQIMEREIENIQTYQSTAEEN
  FLQEIKNAKSEASIYKNSLSEIGKECEMLSKMVMETKTDNQILKEELKKHSQENIKFENSISRLTEDKILLENYV
  RSIENERDTLEFEMRHLQREYLSLSDKICNQHNDPSKTTYISRREKFHFDNYTHEDTSSPQSRPLASDLKGYFKV
  KDRTLKHH

• Structural information:
  • STRING: ENSP00000306776
• Other Databases: GeneCards:  CCDC110  Malacards:  CCDC110

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005856	cytoskeleton	IBA	cellular component
GO:0005634	nucleus	IEA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005634	nucleus	IEA	cellular component

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)