• Gene id: 255374

Gene Summary

• Gene Symbol: MBLAC1   Gene   UCSC   Ensembl
• Gene name: metallo-beta-lactamase domain containing 1
• Alternate names: metallo-beta-lactamase domain-containing protein 1,
• Gene location: 7q22.1 (100126719: 100128494)     Exons: 2     NC_000007.14

Protein Summary

• Protein general information: A4D2B0  
  • Name: Metallo beta lactamase domain containing protein 1 (EC 3. . . )
  • Length: 266  
  • Mass: 27202
• Sequence:

  MRTEPLCGASPLLVPGDPYSVVVLLQGYAEPEGVGDAVRADGSVTLVLPQTRGPASSHRESPRGSGGAEAALEEA
  ARGPILVDTGGPWAREALLGALAGQGVAPGDVTLVVGTHGHSDHIGNLGLFPGAALLVSHDFCLPGGRYLPHGLG
  EGQPLRLGPGLEVWATPGHGGQRDVSVVVAGTALGTVVVAGDVFERDGDEDSWQALSEDPAAQERSRKRVLVVAD
  VVVPGHGPPFRVLREASQPETEGGGNSQQEPVVGDEEPALH

• Structural information:
  • Interpro: IPR039344  IPR001279  IPR036866  
  • PDB: 4V0H
  • PDBsum: 4V0H
  • STRING: ENSP00000381150
• Other Databases: GeneCards:  MBLAC1  Malacards:  MBLAC1

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0016787	hydrolase activity	IEA	molecular function
GO:0046872	metal ion binding	IEA	molecular function

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)