• Gene id: 253935

Gene Summary

• Gene Symbol: ANGPTL5   Gene   UCSC   Ensembl
• Gene name: angiopoietin like 5
• Alternate names: angiopoietin-related protein 5, angiopoietin-like protein 5,
• Gene location: 11q22.1 (94927222: 94896948)     Exons: 10     NC_000001.11
• OMIM: 607666

Protein Summary

• Protein general information: Q86XS5  
  • Name: Angiopoietin related protein 5 (Angiopoietin like protein 5)
  • Length: 388  
  • Mass: 44144
  • Tissue specificity: Mainly expressed in adult heart. {ECO
• Sequence:

  MMSPSQASLLFLNVCIFICGEAVQGNCVHHSTDSSVVNIVEDGSNAKDESKSNDTVCKEDCEESCDVKTKITREE
  KHFMCRNLQNSIVSYTRSTKKLLRNMMDEQQASLDYLSNQVNELMNRVLLLTTEVFRKQLDPFPHRPVQSHGLDC
  TDIKDTIGSVTKTPSGLYIIHPEGSSYPFEVMCDMDYRGGGRTVIQKRIDGIIDFQRLWCDYLDGFGDLLGEFWL
  GLKKIFYIVNQKNTSFMLYVALESEDDTLAYASYDNFWLEDETRFFKMHLGRYSGNAGDAFRGLKKEDNQNAMPF
  STSDVDNDGCRPACLVNGQSVKSCSHLHNKTGWWFNECGLANLNGIHHFSGKLLATGIQWGTWTKNNSPVKIKSV
  SMKIRRMYNPYFK

• Structural information:
  • Protein Domains: (141..38-)
    (/note="Fibrinogen-C-terminal)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00739"-)
  • Interpro: IPR036056  IPR002181  IPR020837  
  • Prosite: PS00514 PS51406
  • CDD: cd00087
  • DIP: 59887
  • STRING: ENSP00000335255
• Other Databases: GeneCards:  ANGPTL5  Malacards:  ANGPTL5

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005615	extracellular space	IBA	cellular component
GO:0062023	collagen-containing extracellular matrix	IBA	cellular component
GO:0005576	extracellular region	IEA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005576	extracellular region	IEA	cellular component

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)