|
Gene id |
246777 |
| Gene Summary Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
SPESP1 Gene UCSC Ensembl |
|
Aliases |
ESP, SP-ESP |
|
Gene name |
sperm equatorial segment protein 1 |
|
Alternate names |
sperm equatorial segment protein 1, equatorial segment protein, glycosylated 38 kDa sperm protein C-7/8, |
|
Gene location |
15q23 (68930524: 68946810) Exons: 2 NC_000015.10
|
|
Gene summary(Entrez) |
The encoded protein is a human alloantigen involved in sperm-egg binding and fusion. [provided by RefSeq, Apr 2010]
|
|
OMIM |
609399 |
|
| Associated diseases |
References |
| Necessary to produce the fully 'fusion competent' sperm | MIK: 20375058 |
| Plays a crucial role in speramtogenesis | MIK: 25761597 |
| Hypospermatogenesis | MIK: 28361989 |
| Necessary to produce the fully 'fusion competent' sperm | MIK: 20375058 |
| Spermatogenic defects | MIK: 25761597 |
| Teratozoospermia | MIK: 17327269 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 20375058 |
Necessary
to produce
the fully
'fusion c
ompetent'
sperm
|
|
|
|
Male infertility |
|
Show abstract |
| 25761597 |
Plays a ro
le in sper
miogenesis
|
|
|
|
Male infertility |
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
19 (6 controls
, 13 cases)
|
Male infertility |
GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 28361989 |
Hyposperma
togenesis
|
|
|
6 (3 controls,
3 Klienfelter s
yndrome
|
Male infertility |
Microarray
|
Show abstract |
|