|
Gene id |
23788 |
| Gene Summary Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
MTCH2 Gene UCSC Ensembl |
|
Aliases |
HSPC032, MIMP, SLC25A50 |
|
Gene name |
mitochondrial carrier 2 |
|
Alternate names |
mitochondrial carrier homolog 2, 2310034D24Rik, met-induced mitochondrial protein, solute carrier family 25, member 50, |
|
Gene location |
11p11.2 (47642653: 47604308) Exons: 14 NC_000011.10
|
|
Gene summary(Entrez) |
This gene encodes a member of the SLC25 family of nuclear-encoded transporters that are localized in the inner mitochondrial membrane. Members of this superfamily are involved in many metabolic pathways and cell functions. Genome-wide association studies
|
|
OMIM |
613221 |
|
| Associated diseases |
References |
| Obesity | GAD: 19910938 |
| Diabetes | GAD: 19164386 |
| Diabetes | GAD: 19910641 |
| Anorexia nervosa | GAD: 19746409 |
| Polycystic ovary syndrome (PCOS) | INFBASE: 24498077 |
| Associated with apoptosis of spermatocytes | MIK: 25813787 |
| Male infertility | MIK: 25813787 |
| Hypospermatogenesis | MIK: 28361989 |
| Spermatogenic defects | MIK: 31037746 |
| Teratozoospermia | MIK: 17327269 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 25813787 |
Associated
with apop
tosis of s
permatocyt
es, Male i
nfertility
|
|
|
|
Male infertility |
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
19 (6 controls
, 13 cases)
|
Male infertility |
GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 28361989 |
Hyposperma
togenesis
|
|
|
6 (3 controls,
3 Klienfelter s
yndrome
|
Male infertility |
Microarray
|
Show abstract |
| 31037746 |
Spermatoge
nic defect
s
|
|
|
28 men with az
oospermia
|
Male infertility |
Microarray
|
Show abstract |
|