Male Infertility Database

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Gene id

23705

Gene Summary KEGG pathways Diseases PubMed

Gene Summary

Gene Symbol

CADM1 Gene UCSC Ensembl

Aliases

BL2, IGSF4, IGSF4A, NECL2, Necl-2, RA175, ST17, SYNCAM, TSLC1, sTSLC-1, sgIGSF, synCAM1

Gene name

cell adhesion molecule 1

Alternate names

cell adhesion molecule 1, TSLC-1, TSLC1/Nectin-like 2/IGSF4, immunoglobulin superfamily member 4, immunoglobulin superfamily, member 4D variant 1, immunoglobulin superfamily, member 4D variant 2, nectin-like 2, nectin-like protein 2, spermatogenic immunoglobulin,

Gene location

11q23.3 (115504427: 115169235) Exons: 13 NC_000011.10

OMIM

605686

KEGG pathways

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Pathway id	Pathway name
hsa04514	Cell adhesion molecules

Diseases

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Associated diseases	References
Cancer (Nasopharyngeal)	KEGG: H00054
Endometriosis	INFBASE: 22926846
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Abnormal vacuoles in the seminiferous epithelium, showing exfoliation of germ cells, and ultrastructural abnormality of the elongate spermatids	MIK: 21486398
Indispensable for the adhesion of spermatocytes and spermatids to Sertoli cells and for their normal differentiation into mature spermatozoa	MIK: 16612000
May play a role in spermatogenesis	MIK: 12606335
Oligoasthenoteratozoospermia	MIK: 16382161

PubMed references

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PMID	Condition	Population details	Infertility_type	Associated_genes	Abstract
21486398	Abnormal v acuoles in the semin iferous ep ithelium, showing ex foliation of germ ce lls, and u ltrastruct ural abnor mality of the elonga te spermat ids		Male infertility		Show abstract
16612000	Indispensa ble for th e adhesion of sperma tocytes an d spermati ds to Sert oli cells and for th eir normal different iation int o mature s permatozoa		Male infertility		Show abstract
16382161	Oligoasthe noteratozo ospermia		Male infertility		Show abstract
12606335	May play a role in s permatogen esis		Male infertility		Show abstract
21674046	Aberrant C pGs in Low Motility Sperm	18	Male infertility	GSE26881	Show abstract

Male Infertility knowledgebase

A repository with genes crucial for male fertility

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Gene Summary

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Diseases

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PubMed references

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Male Infertility knowledgebase

A repository with genes crucial for male fertility

Search Result

Gene Summary

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Diseases Expand All | Collapse All

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PubMed references

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KEGG pathways

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Diseases

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