• Gene id: 23548

Gene Summary

• Gene Symbol: TTC33   Gene   UCSC   Ensembl
• Aliases: OSRF
• Gene name: tetratricopeptide repeat domain 33
• Alternate names: tetratricopeptide repeat protein 33, TPR repeat protein 33, osmosis responsive factor,
• Gene location: 5p13.1 (40755960: 40711575)     Exons: 5     NC_000005.10
• OMIM: 607519

Protein Summary

• Protein general information: Q6PID6  
  • Name: Tetratricopeptide repeat protein 33 (TPR repeat protein 33) (Osmosis responsive factor)
  • Length: 262  
  • Mass: 29411
• Sequence:

  MASFGWKRKIGEKVSKVTSQQFEAEAADEKDVVDNDEGNWLHAIKRRKEILLEGCAEKSKQLKDEGASLAENKRY
  REAIQKWDEALQLTPNDATLYEMKSQVLMSLHEMFPAVHAAEMAVQQNPHSWESWQTLGRAQLGLGEIILAIRSF
  QVALHIYPMNPEIWKEDLSWARTLQEQQKVAQRIKKSEAPAEVTHFSPKSIPDYDFESDEIVAVCAAIAEKEKTV
  SANKTMVIVSASGAIETVTEKEDGATPPDGSVFIKAR

• Structural information:
  • Interpro: IPR013026  IPR011990  IPR019734  
  • Prosite: PS50005 PS50293
  • STRING: ENSP00000338533
• Other Databases: GeneCards:  TTC33  Malacards:  TTC33

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Cryptorchidism	MIK: 28606200

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq