|
Gene id |
23358 |
| Gene Summary Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
USP24 Gene UCSC Ensembl |
|
Gene name |
ubiquitin specific peptidase 24 |
|
Alternate names |
ubiquitin carboxyl-terminal hydrolase 24, deubiquitinating enzyme 24, ubiquitin specific protease 24, ubiquitin thioesterase 24, ubiquitin thiolesterase 24, ubiquitin-specific processing protease 24, |
|
Gene location |
1p32.3 (55215373: 55066358) Exons: 73 NC_000010.11
|
|
Gene summary(Entrez) |
Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP24 belongs to a large family of cysteine proteases that function as
|
|
OMIM |
610569 |
|
| Associated diseases |
References |
| Coronary heart disease | GAD: 21347282 |
| Albuminuria | GAD: 17903292 |
| Parkinson disease | GAD: 16917932 |
| Spermatogenesis defects | MIK: 29738159 |
| Cryptorchidism | MIK: 28606200 |
| Male infertility | MIK: 26361204 |
| Embryo quality | MIK: 26361204 |
| Spermatogenetic defects | MIK: 29738159 |
| Teratozoospermia | MIK: 17327269 |
| Unexplained infertility | MIK: 25753583 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 29738159 |
Spermatoge
netic defe
cts, Male
infertilit
y
|
|
|
|
Male infertility |
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
19 (6 controls
, 13 cases)
|
Male infertility |
GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 28606200 |
Cryptorchi
dism
|
|
|
Monozgotic twin
s (1 control, I
cwith cryptorc
hidism)
|
Male infertility |
MeDIP-Seq
|
Show abstract |
| 25753583 |
Unexplaine
d infertil
ity
|
|
|
46 (17 fertile
men, 29 male pa
tients)
|
Male infertility |
Microarray
|
Show abstract |
| 26361204 |
Male infer
tility, Em
bryo quali
ty
|
|
|
181 (127 men un
dergoing IVF tr
eatment, 54 nor
mozoospermic, f
ertile men)
|
Male infertility |
Microarray
|
Show abstract |
|