|
Gene id |
22871 |
| Gene Summary KEGG pathways Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
NLGN1 Gene UCSC Ensembl |
|
Aliases |
NL1 |
|
Gene name |
neuroligin 1 |
|
Alternate names |
neuroligin-1, |
|
Gene location |
3q26.31 (173395928: 174294371) Exons: 14 NC_000004.12
|
|
Gene summary(Entrez) |
This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. [provided b
|
|
OMIM |
600568 |
|
| Pathway id | Pathway name |
|---|
| hsa04514 | Cell adhesion molecules | | hsa04514 | Cell adhesion molecules | |
|
| Associated diseases |
References |
| Amyotrophic lateral sclerosis (ALS) | GAD: 18987618 |
| Schizophrenia | GAD: 19736351 |
| Psychological disorders | GAD: 20398908 |
| Several psychiatric disorders | GAD: 19086053 |
| Depression | GAD: 20516156 |
| Autism | GAD: 19598235 |
| Modulates the processes of fertilization and early embryonic development in vivo | MIK: 15121861 |
| Associated with sperm function | MIK: 15121861 |
| Associated with sperm function, modulates the processes of fertilization and early embryonic development in vivo | MIK: 15121861 |
| Cryptorchidism | MIK: 28606200 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 15121861 |
Associated
with sper
m function
, modulate
s the proc
esses of f
ertilizati
on and ear
ly embryon
ic develop
ment in vi
vo
|
|
|
|
Male infertility |
|
Show abstract |
| 28606200 |
Cryptorchi
dism
|
|
|
Monozgotic twin
s (1 control, I
cwith cryptorc
hidism)
|
Male infertility |
MeDIP-Seq
|
Show abstract |
|