• Gene id: 222950

Gene Summary

• Gene Symbol: NYAP1   Gene   UCSC   Ensembl
• Aliases: C7orf51
• Gene name: neuronal tyrosine phosphorylated phosphoinositide-3-kinase adaptor 1
• Alternate names: neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 1,
• Gene location: 7q22.1 (100483926: 100494801)     Exons: 7     NC_000007.14
• OMIM: 600935

Protein Summary

• Protein general information: Q6ZVC0  
  • Name: Neuronal tyrosine phosphorylated phosphoinositide 3 kinase adapter 1
  • Length: 841  
  • Mass: 87928
• Sequence:

  MNLLYRKTKLEWRQHKEEEAKRSSSKEVAPAGSAGPAAGQGPGVRVRDIASLRRSLRMGFMTMPASQEHTPHPCR
  SAMAPRSLSCHSVGSMDSVGGGPGGASGGLTEDSSTRRPPAKPRRHPSTKLSMVGPGSGAETPPSKKAGSQKPTP
  EGRESSRKVPPQKPRRSPNTQLSVSFDESCPPGPSPRGGNLPLQRLTRGSRVAGDPDVGAQEEPVYIEMVGDVFR
  GGGRSGGGLAGPPLGGGGPTPPAGADSDSEESEAIYEEMKYPLPEEAGEGRANGPPPLTATSPPQQPHALPPHAH
  RRPASALPSRRDGTPTKTTPCEIPPPFPNLLQHRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPAGSTPAPQV
  PARERETPPPPPPPPAANLLLLGPSGRARSHSTPLPPQGSGQPRGERELPNSHSMICPKAAGAPAAPPAPAALLP
  GPPKDKAVSYTMVYSAVKVTTHSVLPAGPPLGAGEPKTEKEISVLHGMLCTSSRPPVPGKTSPHGGAMGAAAGVL
  HHRGCLASPHSLPDPTVGPLTPLWTYPATAAGLKRPPAYESLKAGGVLNKGCGVGAPSPMVKIQLQEQGTDGGAF
  ASISCAHVIASAGTPEEEEEEVGAATFGAGWALQRKVLYGGRKAKELDKVEDGARAWNGSAEGPGKVEREDRGPG
  TSGIPVRSQGAEGLLARIHHGDRGGSRTALPIPCQTFPACHRNGDFTGGYRLGRSASTSGVRQVVLHTPRPCSQP
  RDALSQPHPALPLPLPLPPQPARERDGKLLEVIERKRCVCKEIKARHRPDRGLCKQESMPILPSWRRGPEPRKSG
  TPPCRRQHTVLWDTAI

• Structural information:
  • Interpro: IPR026724  IPR026722  IPR029353  IPR039482  
  • STRING: ENSP00000300179
• Other Databases: GeneCards:  NYAP1  Malacards:  NYAP1

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0014065	phosphatidylinositol 3-kinase signaling	IEA	biological process
GO:0048812	neuron projection morphogenesis	IEA	biological process
GO:0014065	phosphatidylinositol 3-kinase signaling	IEA	biological process
GO:0048812	neuron projection morphogenesis	IEA	biological process
GO:0048812	neuron projection morphogenesis	ISS	biological process
GO:0014065	phosphatidylinositol 3-kinase signaling	ISS	biological process

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Cryptorchidism	MIK: 28606200

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq