• Gene id: 221481

Gene Summary

• Gene Symbol: ARMC12   Gene   UCSC   Ensembl
• Aliases: C6orf81
• Gene name: armadillo repeat containing 12
• Alternate names: armadillo repeat-containing protein 12,
• Gene location: 6p21.31 (35733725: 35749078)     Exons: 17     NC_000006.12

Protein Summary

• Protein general information: Q5T9G4  
  • Name: Armadillo repeat containing protein 12
  • Length: 340  
  • Mass: 38632
• Sequence:

  MGKSIPQYLGQLDIRKSVVSLATGAGAIYLLYKAIKAGIKCKPPLCSNSPICIARLAVERERHGRDSGELRRLLN
  SLECKQDEYAKSMILHSITRCVYLLEAEASACTTDDIVLLGYMLDDKDNSVKTQALNTLKAFSGIRKFRLKIQEH
  SIKVLELISTIWDTELHIAGLRLLNNLPLPDYVHPQLRRVMPALMEILQSDYILAQVQAVRLLSYLAQKNDLLYD
  ILNCQVHSNFLNLFQPTQSGSLLYEVLVFAERLSEGRNAPHYHVVKWHYNEQSLHESLFGEESRLADRLLALVIH
  PEEDVQIQACKVIVSLQYPQDLRARPSSCQPSRSYFKNTE

• Structural information:
  • Interpro: IPR011989  IPR006911  IPR016024  IPR042834  
  • STRING: ENSP00000288065
• Other Databases: GeneCards:  ARMC12  Malacards:  ARMC12

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005634	nucleus	HDA	cellular component

Diseases

Associated diseases	References
Non obstructive azoospermia	MIK: 24012201
Sertoli cell only syndrome	MIK: 23869807
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
24012201	Non obstructive azoospermia			31 (4 controls, 27 cases)	Male infertility	GSE45885 analyzed by GEO2R (cutoff 1.5 fold)
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
23869807	Non obstructive azoospermia, Sertoli cell only syndrome			20 (4 controls, 16 cases)	Male infertility	GSE45887 analyzed by GEO2R (cutoff 1.5 fold)