• Gene id: 220382

Gene Summary

• Gene Symbol: FAM181B   Gene   UCSC   Ensembl
• Gene name: family with sequence similarity 181 member B
• Alternate names: protein FAM181B,
• Gene location: 11q14.1 (82733863: 82729939)     Exons: 1     NC_000011.10

Protein Summary

• Protein general information: A6NEQ2  
  • Name: Protein FAM181B
  • Length: 426  
  • Mass: 42657
• Sequence:

  MAVQAALLSTHPFVPFGFGGSPDGLGGAFGALDKGCCFEDDETGAPAGALLSGAEGGDVREATRDLLSFIDSASS
  NIKLALDKPGKSKRKVNHRKYLQKQIKRCSGLMGAAPPGPPSPSAADTPAKRPLAAPSAPTVAAPAHGKAAPRRE
  ASQAAAAASLQSRSLAALFDSLRHVPGGAEPAGGEVAAPAAGLGGAGTGGAGGDVAGPAGATAIPGARKVPLRAR
  NLPPSFFTEPSRAGGGGCGPSGPDVSLGDLEKGAEAVEFFELLGPDYGAGTEAAVLLAAEPLDVFPAGASVLRGP
  PELEPGLFEPPPAVVGNLLYPEPWSVPGCSPTKKSPLTAPRGGLTLNEPLSPLYPAAADSPGGEDGRGHLASFAP
  FFPDCALPPPPPPHQVSYDYSAGYSRTAYSSLWRSDGVWEGAPGEEGAHRD

• Structural information:
  • Interpro: IPR029359  
  • PDB: 6SEO
  • PDBsum: 6SEO
  • STRING: ENSP00000365295
• Other Databases: GeneCards:  FAM181B  Malacards:  FAM181B

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)