• Gene id: 220047

Gene Summary

• Gene Symbol: CCDC83   Gene   UCSC   Ensembl
• Aliases: CT148, HSD9, KP-CoT-23
• Gene name: coiled-coil domain containing 83
• Alternate names: coiled-coil domain-containing protein 83,
• Gene location: 11q14.1-q14.2 (85855065: 85920016)     Exons: 15     NC_000011.10

Protein Summary

• Protein general information: Q8IWF9  
  • Name: Coiled coil domain containing protein 83
  • Length: 413  
  • Mass: 48851
• Sequence:

  MENSGKANKKDTHDGPPKEIKLPTSEALLDYQCQIKEDAVEQFMFQIKTLRKKNQKYHERNSRLKEEQIWHIRHL
  LKELSEEKAEGLPVVTREDVEEAMKEKWKFERDQEKNLRDMRMQISNAEKLFLEKLSEKEYWEEYKNVGSERHAK
  LITSLQNDINTVKENAEKMSEHYKITLEDTRKKIIKETLLQLDQKKEWATQNAVKLIDKGSYLEIWENDWLKKEV
  AIHRKEVEELKNAIHELEAENLVLIDQLSNCRLVDLKIPRRLYLTQAAGLEVPPEEMSLELPETHIEEKSELQPT
  EVESRDLMSSSDESTILHLSHENSIEDLQYVKIDKEENSGTEFGDTDMKYLLYEDEKDFKDYVNLGPLGVKLMSV
  ESKKMPIHFQEKEIPVKLYKDVRSPESHITYKMMKSFL

• Structural information:
  • Interpro: IPR026702  
  • STRING: ENSP00000280245
• Other Databases: GeneCards:  CCDC83  Malacards:  CCDC83

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005515	protein binding	IPI	molecular function

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881