• Gene id: 219938

Gene Summary

• Gene Symbol: SPATA19   Gene   UCSC   Ensembl
• Aliases: CT132, SPAS1, spergen1
• Gene name: spermatogenesis associated 19
• Alternate names: spermatogenesis-associated protein 19, mitochondrial, cancer/testis antigen 132, spergen-1, spermatogenic cell-specific gene 1 protein, spermatogenic specific-gene1, testis secretory sperm-binding protein Li 243mP,
• Gene location: 11q25 (133845532: 133835929)     Exons: 8     NC_000011.10
• OMIM: 609805

Protein Summary

• Protein general information: Q7Z5L4  
  • Name: Spermatogenesis associated protein 19, mitochondrial (Spermatogenic cell specific gene 1 protein) (Spergen 1)
  • Length: 167  
  • Mass: 19186
  • Tissue specificity: Expressed specifically in testis. {ECO
• Sequence:

  MIITTWIVYILARKGVGLPFLPITSSDIDVVESEAVSVLHHWLKKTEEEASRGIKEKLSINHPSQGVREKMSTDS
  PPTHGQDIHVTRDVVKHHLSKSDLLANQSQEVLEERTRIQFIRWSHTRIFQVPSEMTEDIMRDRIEQVRRSISRL
  TDVSAQDFSMRPSSSDC

• Structural information:
  • Interpro: IPR028219  
  • STRING: ENSP00000299140
• Other Databases: GeneCards:  SPATA19  Malacards:  SPATA19

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0007283	spermatogenesis	IEA	biological process
GO:0030154	cell differentiation	IEA	biological process
GO:0016020	membrane	IEA	cellular component
GO:0005741	mitochondrial outer membrane	IEA	cellular component
GO:0007275	multicellular organism development	IEA	biological process
GO:0005739	mitochondrion	IEA	cellular component
GO:0005741	mitochondrial outer membrane	IEA	cellular component

Diseases

Associated diseases	References
Non obstructive azoospermia	MIK: 24012201
Sertoli cell only syndrome	MIK: 23869807
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
24012201	Non obstructive azoospermia			31 (4 controls, 27 cases)	Male infertility	GSE45885 analyzed by GEO2R (cutoff 1.5 fold)
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
23869807	Non obstructive azoospermia, Sertoli cell only syndrome			20 (4 controls, 16 cases)	Male infertility	GSE45887 analyzed by GEO2R (cutoff 1.5 fold)