|
Gene id |
219743 |
| Gene Summary Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
TYSND1 Gene UCSC Ensembl |
|
Aliases |
NET41 |
|
Gene name |
trypsin domain containing 1 |
|
Alternate names |
peroxisomal leader peptide-processing protease, peroxisomal cysteine endopeptidase, trypsin domain-containing protein 1, |
|
Gene location |
10q22.1 (70146739: 70137980) Exons: 5 NC_000005.10
|
|
Gene summary(Entrez) |
This gene encodes a protease that removes the N-terminal peroxisomal targeting signal (PTS2) from proteins produced in the cytosol, thereby facilitating their import into the peroxisome. The encoded protein is also capable of removing the C-terminal perox
|
|
OMIM |
611017 |
|
| Associated diseases |
References |
| Alzheimer's disease | GAD: 16385451 |
| Male factor infertility | MIK: 23459139 |
| Male infertility | MIK: 23459139 |
| Teratozoospermia | MIK: 17327269 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 23459139 |
Male infer
tility
|
|
|
|
Male infertility |
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
19 (6 controls
, 13 cases)
|
Male infertility |
GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
|