• Gene id: 219654

Gene Summary

• Gene Symbol: ZCCHC24   Gene   UCSC   Ensembl
• Aliases: C10orf56, Z3CXXC8
• Gene name: zinc finger CCHC-type containing 24
• Alternate names: zinc finger CCHC domain-containing protein 24, zinc finger, 3CxxC-type 8, zinc finger, CCHC domain containing 24,
• Gene location: 10q22.3 (79445623: 79382324)     Exons: 5     NC_000010.11
• OMIM: 615136

Protein Summary

• Protein general information: Q8N2G6  
  • Name: Zinc finger CCHC domain containing protein 24
  • Length: 241  
  • Mass: 26955
• Sequence:

  MSLLSAIDTSAASVYQPAQLLNWVYLSLQDTHQASAFDAFRPEPTAGAAPPELAFGKGRPEQLGSPLHSSYLNSF
  FQLQRGEALSNSVYKGASPYGSLNNIADGLSSLTEHFSDLTLTSEARKPSKRPPPNYLCHLCFNKGHYIKDCPQA
  RPKGEGLTPYQGKKRCFGEYKCPKCKRKWMSGNSWANMGQECIKCHINVYPHKQRPLEKPDGLDVSDQSKEHPQH
  LCEKCKVLGYYCRRVQ

• Structural information:
  • Interpro: IPR033446  IPR025829  IPR027377  IPR001878  IPR036875  
  • Prosite: PS50158
  • STRING: ENSP00000361411
• Other Databases: GeneCards:  ZCCHC24  Malacards:  ZCCHC24

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0008270	zinc ion binding	IEA	molecular function
GO:0003676	nucleic acid binding	IEA	molecular function
GO:0046872	metal ion binding	IEA	molecular function
GO:0003723	RNA binding	HDA	molecular function

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Cryptorchidism	MIK: 28606200
Spermatogenic defects	MIK: 31037746
Spermatogenic defects	MIK: 31037746

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq
31037746	Spermatogenic defects			28 men with azoospermia	Male infertility	Microarray
31037746	Spermatogenic defects			16 (1 control, 15 cases)	Male infertility	GSE6023 analyzed using GEO2R