|
Gene id |
2150 |
| Gene Summary Protein Summary Gene ontology KEGG pathways Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
F2RL1 Gene UCSC Ensembl |
|
Aliases |
GPR11, PAR2 |
|
Gene name |
F2R like trypsin receptor 1 |
|
Alternate names |
proteinase-activated receptor 2, G-protein coupled receptor 11, coagulation factor II (thrombin) receptor-like 1, protease-activated receptor 2, thrombin receptor-like 1, |
|
Gene location |
5q13.3 (76819029: 76835314) Exons: 3 NC_000005.10
|
|
Gene summary(Entrez) |
This gene encodes a member of the G-protein coupled receptor 1 family of proteins. The encoded cell surface receptor is activated through proteolytic cleavage of its extracellular amino terminus, resulting in a new amino terminus that acts as a tethered l
|
|
OMIM |
600933 |
Protein Summary
|
|
| GO accession | Term name | Evidence code | Go category |
|---|
|
|
| Pathway id | Pathway name |
|---|
| hsa04080 | Neuroactive ligand-receptor interaction | | hsa04750 | Inflammatory mediator regulation of TRP channels | | hsa05143 | African trypanosomiasis | |
|
| Associated diseases |
References |
| Assocaited with sperm motility | MIK: 17712488 |
| Spermatogenic defects | MIK: 31037746 |
| Teratozoospermia | MIK: 17327269 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 17712488 |
Assocaited
with sper
m motility
|
|
|
15 healthy seme
n donors
|
Male infertility |
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
13 (5 controls,
8 cases)
|
Male infertility |
GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 31037746 |
Spermatoge
nic defect
s
|
|
|
16 (1 control,
15 cases)
|
Male infertility |
GSE6023 analyzed using GEO2R
|
Show abstract |
|