|
Gene id |
2145 |
| Gene Summary Protein Summary Gene ontology KEGG pathways Diseases PubMed |
Gene Summary
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|
Gene Symbol |
EZH1 Gene UCSC Ensembl |
|
Aliases |
KMT6B |
|
Gene name |
enhancer of zeste 1 polycomb repressive complex 2 subunit |
|
Alternate names |
histone-lysine N-methyltransferase EZH1, ENX-2, enhancer of zeste homolog 1, |
|
Gene location |
17q21.2 (42745077: 42700274) Exons: 21 NC_000024.10
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|
Gene summary(Entrez) |
EZH1 is a component of a noncanonical Polycomb repressive complex-2 (PRC2) that mediates methylation of histone H3 (see MIM 602812) lys27 (H3K27) and functions in the maintenance of embryonic stem cell pluripotency and plasticity (Shen et al., 2008 [PubMe
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|
OMIM |
601674 |
Protein Summary
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| GO accession | Term name | Evidence code | Go category |
|---|
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| Associated diseases |
References |
| Head and neck cancer | GAD: 20819778 |
| Meiotic arrest in spermatocytes | MIK: 28254491 |
| Aberrant CpGs in Low Motility Sperm | MIK: 21674046 |
| Meiotic arrest in spermatocytes | MIK: 28254491 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 28254491 |
Meiotic ar
rest in sp
ermatocyte
s
|
|
|
|
Male infertility |
|
Show abstract |
| 21674046 |
Aberrant C
pGs in Low
Motility
Sperm
|
|
|
18
|
Male infertility |
GSE26881
|
Show abstract |
|