|
Gene id |
203074 |
| Gene Summary Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
PRSS55 Gene UCSC Ensembl |
|
Aliases |
CT153, T-SP1, TSP1, UNQ9391 |
|
Gene name |
serine protease 55 |
|
Alternate names |
serine protease 55, probable serine protease UNQ9391/PRO34284, protease, serine 55, testis serine protease 1, tryptophan/serine protease, |
|
Gene location |
8p23.1 (10525483: 10554165) Exons: 10 NC_000009.12
|
|
Gene summary(Entrez) |
This gene encodes a member of a group of membrane-anchored chymotrypsin (S1)-like serine proteases. The enocoded protein is primarily expressed in the Leydig and Sertoli cells of the testis and may be involved in male fertility. Alternate splicing results
|
|
OMIM |
615144 |
|
| Associated diseases |
References |
| Affects sperm migration and sperm-egg binding | MIK: 30032357 |
| Aberrant CpGs in Low Motility Sperm | MIK: 21674046 |
| Affects sperm migration and sperm-egg binding | MIK: 30032357 |
| Male infertility | MIK: 30032357 |
| Cryptorchidism | MIK: 28606200 |
| Spermatogenic defects | MIK: 31037746 |
| Spermatogenic defects | MIK: 31037746 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 30032357 |
Affects sp
erm migrat
ion and sp
erm-egg bi
nding, Mal
e infertil
ity
|
|
|
|
Male infertility |
PRSS55
ADAM3
|
Show abstract |
| 21674046 |
Aberrant C
pGs in Low
Motility
Sperm
|
|
|
18
|
Male infertility |
GSE26881
|
Show abstract |
| 28606200 |
Cryptorchi
dism
|
|
|
Monozgotic twin
s (1 control, I
cwith cryptorc
hidism)
|
Male infertility |
MeDIP-Seq
|
Show abstract |
| 31037746 |
Spermatoge
nic defect
s
|
|
|
28 men with az
oospermia
|
Male infertility |
Microarray
|
Show abstract |
| 31037746 |
Spermatoge
nic defect
s
|
|
|
16 (1 control,
15 cases)
|
Male infertility |
GSE6023 analyzed using GEO2R
|
Show abstract |
|