• Gene id: 201965

Gene Summary

• Gene Symbol: RWDD4   Gene   UCSC   Ensembl
• Aliases: FAM28A, RWDD4A
• Gene name: RWD domain containing 4
• Alternate names: RWD domain-containing protein 4, RWD domain containing 4A, RWD domain-containing protein 4A, family with sequence similarity 28, member A,
• Gene location: 4q35.1 (183659217: 183639634)     Exons: 8     NC_000004.12

Protein Summary

• Protein general information: Q6NW29  
  • Name: RWD domain containing protein 4 (Protein FAM28A)
  • Length: 188  
  • Mass: 21251
• Sequence:

  MSANEDQEMELEALRSIYEGDESFRELSPVSFQYRIGENGDPKAFLIEISWTETYPQTPPILSMNAFFNNTISSA
  VKQSILAKLQEAVEANLGTAMTYTLFEYAKDNKEQFMENHNPINSATSISNIISIETPNTAPSSKKKDKKEQLSK
  AQKRKLADKTDHKGELPRGWNWVDVVKHLSKTGSKDDE

• Structural information:
  • Protein Domains: (9..11-)
    (/note="RWD-)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00179"-)
  • Interpro: IPR006575  IPR042770  IPR016135  
  • Prosite: PS50908
  • STRING: ENSP00000388920
• Other Databases: GeneCards:  RWDD4  Malacards:  RWDD4

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function

Diseases

Associated diseases	References
Hypospermatogenesis	MIK: 28361989
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
28361989	Hypospermatogenesis			6 (3 controls, 3 Klienfelter syndrome	Male infertility	Microarray