• Gene id: 201191

Gene Summary

• Gene Symbol: SAMD14   Gene   UCSC   Ensembl
• Gene name: sterile alpha motif domain containing 14
• Alternate names: sterile alpha motif domain-containing protein 14, SAM domain-containing protein 14,
• Gene location: 17q21.33 (50130159: 50110039)     Exons: 14     NC_000017.11
• OMIM: 610652

Protein Summary

• Protein general information: Q8IZD0  
  • Name: Sterile alpha motif domain containing protein 14 (SAM domain containing protein 14)
  • Length: 417  
  • Mass: 45056
• Sequence:

  MASSKLREPVDEVFDLDLAVPETARLDSSLHKARAQLLAKGRRHRPSRSRLRDSASSAEDGEGSDGPGGKVTDGC
  GSPLHRLRSPLHSGPGSPAGGSFCLDPPGLRRSLDEDEPPPSPLTRYRPLHNAASHEGLAAASCSPPRSAPSSDS
  SPSFVRRHPRAEPHSEDDSRDASPPEPASPTIGLDKKTRRKFLDLGVTLRRASTGKSRKEKGSNRLSMGSRESVE
  GSGRSGGSPFLPFSWFTDSGKGSASSGSTTSPTCSPKHEGFSPKKSASQESTLSDDSTPPSSSPKIPSGPWQEAK
  CSYPYHTLSQSSDEFLDEPLPPVHHWTSQQVGQWLQSLNLEQYAAEFAARQVDGPQLLQLDGSKLKSLGLSNSHD
  RALVKRKLKEMAAAAEKERKAQEKAARQREKLRRREQEAKKS

• Structural information:
  • Protein Domains: (326..38-)
    (/note="SAM-)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00184"-)
  • Interpro: IPR001660  IPR013761  
  • Prosite: PS50105
  • STRING: ENSP00000424474
• Other Databases: GeneCards:  SAMD14  Malacards:  SAMD14

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0007015	actin filament organization	IBA	biological process
GO:0015629	actin cytoskeleton	IBA	cellular component
GO:0030425	dendrite	IBA	cellular component
GO:0031175	neuron projection development	IBA	biological process
GO:0051015	actin filament binding	IBA	molecular function
GO:0005737	cytoplasm	IBA	cellular component
GO:0014069	postsynaptic density	IBA	cellular component
GO:0019722	calcium-mediated signaling	IBA	biological process

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Cryptorchidism	MIK: 28606200

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq