|
Gene id |
199720 |
| Gene Summary Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
GGN Gene UCSC Ensembl |
|
Gene name |
gametogenetin |
|
Alternate names |
gametogenetin, |
|
Gene location |
19q13.2 (38388602: 38384266) Exons: 5 NC_000004.12
|
|
Gene summary(Entrez) |
This gene is a germ cell-specific gene that encodes proteins that interact with POG (proliferation of germ cells). Alternatively spliced transcript variants of a similar mouse gene encode at least three different proteins, namely gametogenetin protein 1a,
|
|
OMIM |
609966 |
|
| Associated diseases |
References |
| Plays a crucial role in speramtogenesis | MIK: 12574169 |
| Cryptorchidism | MIK: 28606200 |
| Globozoospermia | MIK: 31985809 |
| Non obstructive azoospermia | MIK: 24012201 |
| Sertoli cell only syndrome | MIK: 23869807 |
| Spermatogenic defects | MIK: 12574169 |
| Teratozoospermia | MIK: 17327269 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 12574169 |
Plays a ro
le in sper
matogenesi
s
|
|
|
|
Male infertility |
|
Show abstract |
| 24012201 |
Non obstru
ctive azoo
spermia
|
|
|
31 (4 controls,
27 cases)
|
Male infertility |
GSE45885 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
19 (6 controls
, 13 cases)
|
Male infertility |
GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 23869807 |
Non obstru
ctive azoo
spermia, S
ertoli cel
l only syn
drome
|
|
|
20 (4 controls,
16 cases)
|
Male infertility |
GSE45887 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 28606200 |
Cryptorchi
dism
|
|
|
Monozgotic twin
s (1 control, I
cwith cryptorc
hidism)
|
Male infertility |
MeDIP-Seq
|
Show abstract |
| 31985809 |
Globozoosp
ermia
|
p.(Gly424Alafs*65) |
|
16 infertile pa
tients
|
Male infertility |
NGS
|
Show abstract |
|