• Gene id: 167410

Gene Summary

• Gene Symbol: LIX1   Gene   UCSC   Ensembl
• Aliases: C5orf11, Lft
• Gene name: limb and CNS expressed 1
• Alternate names: protein limb expression 1 homolog, Lix1 homolog, Lowfat homolog, limb expression 1,
• Gene location: 5q15 (97142610: 97091866)     Exons: 6     NC_000005.10

Protein Summary

• Protein general information: Q8N485  
  • Name: Protein limb expression 1 homolog
  • Length: 282  
  • Mass: 31891
• Sequence:

  MDRTLESLRHIIAQVLPHRDPALVFKDLNVVSMLQEFWESKQQQKAAFPSEGVVVYESLPAPGPPFVSYVTLPGG
  SCFGNFQCCLSRAEARRDAAKVALINSLFNELPSRRITKEFIMESVQEAVASTSGTLDDADDPSTSVGAYHYMLE
  SNMGKTMLEFQELMTIFQLLHWNGSLKALRETKCSRQEVISYYSQYSLDEKMRSHMALDWIMKERDSPGIVSQEL
  RMALRQLEEARKAGQELRFYKEKKEILSLALTQICSDPDTSSPSDDQLSLTALCGYH

• Structural information:
  • Interpro: IPR029270  
  • STRING: ENSP00000274382
• Other Databases: GeneCards:  LIX1  Malacards:  LIX1

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005737	cytoplasm	IBA	cellular component
GO:0006914	autophagy	IBA	biological process
GO:0097352	autophagosome maturation	IBA	biological process
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005737	cytoplasm	IBA	cellular component
GO:0006914	autophagy	IBA	biological process
GO:0097352	autophagosome maturation	IBA	biological process
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881