• Gene id: 165186

Gene Summary

• Gene Symbol: TOGARAM2   Gene   UCSC   Ensembl
• Aliases: FAM179A
• Gene name: TOG array regulator of axonemal microtubules 2
• Alternate names: TOG array regulator of axonemal microtubules protein 2, crescerin-2, family with sequence similarity 179 member A, protein FAM179A,
• Gene location: 2p23.2 (28981297: 29052229)     Exons: 27     NC_000002.12

Protein Summary

• Protein general information: Q6ZUX3  
  • Name: TOG array regulator of axonemal microtubules protein 2 (Crescerin 2)
  • Length: 1019  
  • Mass: 111153
• Sequence:

  MGTRDDVPEAKVLVPVAVYCGSIPRTSAGPRVLPPGSINSSLPHGEGSLQPEPRALLNNEEPSQLLRGLGQLGGL
  KLDTPSKGWQARNGHPRNLRALSLGDQPLVLLPSPESEANSVARDTIQIKDKLKKRRLSEGLAASSRASLDPGGG
  PQGVPLHSTIPRATSQRLLRVPRPMPLIQSIPTTPEASGVKEKGLDLPGSIPGPHELRPGAQEAQISWQYLHCND
  EKMQKSLGAIVIPPIPKARTVAATPSRVPGSLPSPLPPGQGVLTGLRAPRTRLARGSGPREKTPASLEPKPLASP
  IRDRPAAAKKPALPFSQSAPTLTAFSFDCAREACPPLKEEDQKEIGTKIQVTISKSAREKMQLKQMKEMELLRRL
  EEPRTGQELTSQCLGSQRAFMKEGLLPLRGSGTLSVPTRLSGPCRNDVSIILRKWASRASLPSIPISRQEPRFAR
  HASANSLPAVLTLGSPEWEEEEEMDLRACKELRPFSNPELGLRDALQCLNSSDWQMKEKGLVSIQRLAACHSEVL
  TGKLHDVCLVVTGEVTNLRSKVSHLAISTLGDLFQALKKNMDQEAEEIARCLLQKMADTNEFIQRAAGQSLRAMV
  ENVTLARSLVVLTSAGVYHRNPLIRKYAAEHLSAVLEQIGAEKLLSGTRDSTDMLVHNLVRLAQDSNQDTRFYGR
  KMVNILMANTKFDAFLKQSLPSYDLQKVMAAIKQQGIEDNDELPSAKGRKVLRSLVVCENGLPIKEGLSCNGPRL
  VGLRSTLQGRGEMVEQLRELTRLLEAKDFRSRMEGVGQLLELCKAKTELVTAHLVQVFDAFTPRLQDSNKKVNQW
  ALESFAKMIPLLRESLHPMLLSIIITVADNLNSKNSGIYAAAVAVLDAMVESLDNLCLLPALAGRVRFLSGRAVL
  DVTDRLAVLVASVYPRKPQAVERHVLPILWHFLNTATRNGTLPGPSGNIRGVVCRLSRSLQEHMGSRLLDFAASQ
  PKHVLKTLQELLDSESLGGSRKATDRGVAPDSKTTGSSYPFQLD

• Structural information:
  • Interpro: IPR011989  IPR016024  IPR024395  IPR034085  
  • STRING: ENSP00000368876
• Other Databases: GeneCards:  TOGARAM2  Malacards:  TOGARAM2

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0008017	microtubule binding	IBA	molecular function
GO:0005929	cilium	IBA	cellular component
GO:0005881	cytoplasmic microtubule	IBA	cellular component
GO:0000226	microtubule cytoskeleton organization	IBA	biological process

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq