• Gene id: 162073

Gene Summary

• Gene Symbol: ITPRIPL2   Gene   UCSC   Ensembl
• Gene name: ITPRIP like 2
• Alternate names: inositol 1,4,5-trisphosphate receptor-interacting protein-like 2, inositol 1,4,5-triphosphate receptor-interacting protein-like 2, inositol 1,4,5-trisphosphate receptor interacting protein like 2,
• Gene location: 16p12.3 (19113931: 19121629)     Exons: 2     NC_000016.10
• OMIM: 602865

Protein Summary

• Protein general information: Q3MIP1  
  • Name: Inositol 1,4,5 trisphosphate receptor interacting protein like 2
  • Length: 535  
  • Mass: 58446
• Sequence:

  MSVHYTLNLRVFWPLVTGLCTALVCLYHVLRGSGGARAEPADGVDGGFPLLKVAVLLLLSYVLLRCRHAVRQRFL
  PGSPRLEGHAAFSSRHFREPGLSILLESYYEHEVRLSPHVLGHSKAHVSRIVGELVRAGRARGSPGLIPGGALAL
  AFRGDFIQVGSAYEQHKIRRPDSFDVLVPLRLPPLVALEPRSLGEEPALAPAFRGCFLCALKAPPSPSGASGGHW
  LRDCKPFADAFCVDVRGRRHLSATLVLRWFQSHLQRSLATVRYSLEGRCRVTLTPGGLEQPPTLHILPCRTDYGC
  CRLSMAVRLIPAVHLGDGVFLVAPPPPPLPSAPLLELPEGLRAEALWGVNTARQEQKLLSWLQERAAPGACYLKC
  LQLLKALRDLGARGLDSAAATQWGRILSSYVLKTVLLAVLLRKGAPGQGWDEEHLGRCLEELVQFLRDCLLRRHT
  LFHCVLGPGGAAAEVGPLPKALREAAPVDLLAAFDGHARELAAARLLSTWQRLPQLLRAYGGPRYLARCPPPRSQ
  RTQGFLEGEP

• Structural information:
  • Interpro: IPR024798  IPR026250  IPR024810  
  • STRING: ENSP00000370849
• Other Databases: GeneCards:  ITPRIPL2  Malacards:  ITPRIPL2

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0016021	integral component of membrane	IEA	cellular component
GO:0016020	membrane	IEA	cellular component
GO:0016020	membrane	IEA	cellular component

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200
Hypospermatogenesis	MIK: 28361989
Spermatogenic defects	MIK: 31037746

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq
28361989	Hypospermatogenesis			6 (3 controls, 3 Klienfelter syndrome	Male infertility	Microarray
31037746	Spermatogenic defects			16 (1 control, 15 cases)	Male infertility	GSE6023 analyzed using GEO2R