|
Gene id |
161514 |
| Gene Summary Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
TBC1D21 Gene UCSC Ensembl |
|
Aliases |
MgcRabGAP |
|
Gene name |
TBC1 domain family member 21 |
|
Alternate names |
TBC1 domain family member 21, male germ cell-specific expressed, containing a RabGAP domain, |
|
Gene location |
15q24.1 (73873555: 73912165) Exons: 14 NC_000015.10
|
|
OMIM |
0 |
|
| Associated diseases |
References |
| Involved in acrosome formation and cytoskeletal reorganization during spermiogenesis | MIK: 21128978 |
| Important in mammalian spermiogenesis | MIK: 30360518 |
| Aberrant CpGs in Low Motility Sperm | MIK: 21674046 |
| Hypospermatogenesis | MIK: 28361989 |
| Important in mammalian spermiogenesis | MIK: 30360518 |
| Involved in acrosome/acroplaxome formation and cytoskeletal reorganization during spermiogenesis | MIK: 21128978 |
| Azoospermia | MIK: 24012201 |
| Teratozoospermia | MIK: 17327269 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 21128978 |
Involved i
n acrosome
/acroplaxo
me formati
on and cyt
oskeletal
reorganiza
tion durin
g spermiog
enesis
|
|
|
|
Male infertility |
|
Show abstract |
| 28067790 |
Involved i
n mammalia
n spermiog
enesis
|
|
|
|
Male infertility |
|
Show abstract |
| 30360518 |
Important
in mammali
an spermio
genesis
|
|
|
|
Male infertility |
|
Show abstract |
| 24012201 |
Non obstru
ctive azoo
spermia
|
|
|
31 (4 controls,
27 cases)
|
Male infertility |
GSE45885 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
19 (6 controls
, 13 cases)
|
Male infertility |
GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 21674046 |
Aberrant C
pGs in Low
Motility
Sperm
|
|
|
18
|
Male infertility |
GSE26881
|
Show abstract |
| 28361989 |
Hyposperma
togenesis
|
|
|
6 (3 controls,
3 Klienfelter s
yndrome
|
Male infertility |
Microarray
|
Show abstract |
|