• Gene id: 161394

Gene Summary

• Gene Symbol: SAMD15   Gene   UCSC   Ensembl
• Aliases: C14orf174, FAM15A
• Gene name: sterile alpha motif domain containing 15
• Alternate names: sterile alpha motif domain-containing protein 15, SAM domain-containing protein 15, SAM domain-containing protein C14orf174, family with sequence similarity 15, member A,
• Gene location: 14q24.3 (77377377: 77391299)     Exons: 3     NC_000014.9
• OMIM: 0

Protein Summary

• Protein general information: Q9P1V8  
  • Name: Sterile alpha motif domain containing protein 15 (SAM domain containing protein 15)
  • Length: 674  
  • Mass: 77151
• Sequence:

  MAEVPEDYDSGPDEDGELEPERPELPGLHKLYENAEPDTMAKADSKLPAEIYQEPQPETEEEDFKEGEPDSAKNV
  QLKPGGTSQEGIAKESKRDVPSETEPGIHQEVKSETSREMGEFFKDLEAPMDETHKESDLEPPEEAKPNVTEDVF
  LESAMETDPDPVPPTETMSEVSGATVRERNLELLEEETEPGVPEESLRVQHEETGLEPPEQTKQDFPSEKLGESL
  EETDLQPPKMTKPETPEETQRESTEKKRTEPPEQARLEFLEKEPRKSSEEAGLEPPEETQPEVPEEMQRKATEEK
  GTELPERTKPDFPDHKPRKSTDENVPEPLEEIKLEFPEEESRKTNEETILEQSEMMKPESPEEIRKSNEKKNPQP
  PEETGPVLPQEINPQVEEKTQTKPTEKILELPDETKPRETHVEFSKEDRPEPIKSKYSVGNDELEHREPKRGKLS
  LSDKFRKEYYALGSLRESEESIGTHYEFLQPLQKLLNVSEECSYSDPSESQTELSEFVHEKEVVDLSQELKERVS
  EDDETQPEKGTELQFEHLNWDPEEVAEWISQLGFPQYKECFITNFISGRKLIHVNCSNLPQMGITNFEDMKAISR
  HTQELLEIEEPLFKRSISLPYRDIIGLYLEQKGHTGIKSDSLTLSEFVKAAGLQDYAPEITAPEENEELPCTEP

• Structural information:
  • Protein Domains: (545..60-)
    (/note="SAM-)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00184"-)
  • Interpro: IPR001660  IPR013761  IPR042554  
  • Prosite: PS50105
  • STRING: ENSP00000216471
• Other Databases: GeneCards:  SAMD15  Malacards:  SAMD15

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)