• Gene id: 160762

Gene Summary

• Gene Symbol: CCDC63   Gene   UCSC   Ensembl
• Aliases: ODA5
• Gene name: coiled-coil domain containing 63
• Alternate names: coiled-coil domain-containing protein 63, outer row dynein assembly 5 homolog,
• Gene location: 12q24.11 (110844488: 110907534)     Exons: 16     NC_000012.12
• OMIM: 617969

Protein Summary

• Protein general information: Q8NA47  
  • Name: Coiled coil domain containing protein 63
  • Length: 563  
  • Mass: 66250
• Sequence:

  MSVLKKNRRKDSDTPQEPSEKAKEQQAEAELRKLRQQFRKMVESRKSFKFRNQQKIASQYKEIKTLKTEQDEITL
  LLSLMKSSRNMNRSEKNYMELRLLLQTKEDYEALIKSLKVLLAELDEKILQMEKKIANQKQIFAKMQEANNPRKL
  QKQIHILETRLNLVTVHFDKMLTTNAKLRKEIEDLRFEKAAYDNVYQQLQHCLLMEKKTMNLAIEQSSQAYEQRV
  EAMARMAAMKDRQKKDTSQYNLEIRELERLYAHESKLKSFLLVKLNDRNEFEEQAKREEALKAKKHVKKNRGESF
  ESYEVAHLRLLKLAESGNLNQLIEDFLAKEEKNFARFTYVTELNNDMEMMHKRTQRIQDEIILLRSQQKLSHDDN
  HSVLRQLEDKLRKTTEEADMYESKYGEVSKTLDLLKNSVEKLFKKINCDATKILVQLGETGKVTDINLPQYFAII
  EKKTNDLLLLETYRRILEVEGAEAEIPPPFINPFWGGSALLKPPEPIKVIPPVLGADPFSDRLDDVEQPLDHSSL
  RQLVLDNYILKENRSKEVRGDSLPEKVDDFRSRKKVTM

• Structural information:
  • Interpro: IPR029652  
  • STRING: ENSP00000312399
• Other Databases: GeneCards:  CCDC63  Malacards:  CCDC63

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0003341	cilium movement	IBA	biological process
GO:0005930	axoneme	IBA	cellular component
GO:0036158	outer dynein arm assembly	IBA	biological process
GO:0007286	spermatid development	ISS	biological process
GO:0030154	cell differentiation	IEA	biological process
GO:0007283	spermatogenesis	IEA	biological process

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881