|
Gene id |
1587 |
| Gene Summary Protein Summary Gene ontology Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
ADAM3A Gene UCSC Ensembl |
|
Aliases |
ADAM3, CYRN1, tMDCI |
|
Gene name |
ADAM metallopeptidase domain 3A (pseudogene) |
|
Alternate names |
a disintegrin and metalloproteinase domain 3a (cyritestin 1), cyritestin 1, |
|
Gene location |
8p11.22 (39522988: 39451044) Exons: 22 NC_000019.10
|
|
OMIM |
0 |
Protein Summary
|
|
| GO accession | Term name | Evidence code | Go category |
|---|
|
|
| Associated diseases |
References |
| Affects sperm migration and sperm-egg binding | MIK: 30032357 |
| Male factor infertility | MIK: 10569988 |
| Affects sperm migration and sperm-egg binding | MIK: 30032357 |
| Male infertility | MIK: 30032357 |
| Associated with spermatogenesis and epigenetic regulation | MIK: 21674046 |
| Asthenoozoospermia | MIK: 32167074 |
| Hypospermatogenesis | MIK: 28361989 |
| Impairs the migration of sperm into oviduct in mouse | MIK: 19339711 |
| Involved in binding of sperm to the egg zona pellucida | MIK: 15514464 |
| Male infertility | MIK: 10569988 |
| Non obstructive azoospermia | MIK: 24012201 |
| Sertoli cell only syndrome | MIK: 23869807 |
| Spermatogenic defects | MIK: 31037746 |
| Teratozoospermia | MIK: 17327269 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 19339711 |
Impairs th
e migratio
n of sperm
into ovid
uct in mou
se
|
|
|
|
Male infertility |
|
Show abstract |
| 15514464 |
Involved i
n binding
of sperm t
o the egg
zona pellu
cida
|
|
|
|
Male infertility |
|
Show abstract |
| 10569988 |
Male infer
tility
|
|
|
|
Male infertility |
|
Show abstract |
| 30032357 |
Affects sp
erm migrat
ion and sp
erm-egg bi
nding, Mal
e infertil
ity
|
|
|
|
Male infertility |
PRSS55
ADAM3
|
Show abstract |
| 24012201 |
Non obstru
ctive azoo
spermia
|
|
|
31 (4 controls,
27 cases)
|
Male infertility |
GSE45885 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
19 (6 controls
, 13 cases)
|
Male infertility |
GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 23869807 |
Non obstru
ctive azoo
spermia, S
ertoli cel
l only syn
drome
|
|
|
20 (4 controls,
16 cases)
|
Male infertility |
GSE45887 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 21674046 |
Associated
with sper
matogenesi
s and epig
enetic reg
ulation
|
|
|
18
|
Male infertility |
GSE26881
|
Show abstract |
| 28361989 |
Hyposperma
togenesis
|
|
|
6 (3 controls,
3 Klienfelter s
yndrome
|
Male infertility |
Microarray
|
Show abstract |
| 31037746 |
Spermatoge
nic defect
s
|
|
|
28 men with az
oospermia
|
Male infertility |
Microarray
|
Show abstract |
| 31037746 |
Spermatoge
nic defect
s
|
|
|
16 (1 control,
15 cases)
|
Male infertility |
GSE6023 analyzed using GEO2R
|
Show abstract |
| 32167074 |
Asthenoozo
ospermia
|
|
|
12 (6controls,
6 cases)
|
Male infertility |
Microarray
|
Show abstract |
|