• Gene id: 158046

Gene Summary

• Gene Symbol: NXNL2   Gene   UCSC   Ensembl
• Aliases: C9orf121, RDCVF2, RdCVF2L
• Gene name: nucleoredoxin like 2
• Alternate names: nucleoredoxin-like protein 2, rod-derived cone viability factor 2,
• Gene location: 9q22.1 (88535087: 88584509)     Exons: 7     NC_000009.12
• OMIM: 607599

Protein Summary

• Protein general information: Q5VZ03  
  • Name: Nucleoredoxin like protein 2 (Rod derived cone viability factor 2) (RdCVF2)
  • Length: 156  
  • Mass: 17614
• Sequence:

  MVDILGERHLVTCKGATVEAEAALQNKVVALYFAAARCAPSRDFTPLLCDFYTALVAEARRPAPFEVVFVSADGS
  SQEMLDFMRELHGAWLALPFHDPYRHELRKRYNVTAIPKLVIVKQNGEVITNKGRKQIRERGLACFQDWVEAADI
  FQNFSV

• Structural information:
  • Protein Domains: (9..14-)
    (/note="Thioredoxin"-)
  • Interpro: IPR029519  IPR012336  IPR036249  
  • STRING: ENSP00000365014
• Other Databases: GeneCards:  NXNL2  Malacards:  NXNL2

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0007600	sensory perception	IEA	biological process
GO:0045494	photoreceptor cell maintenance	IEA	biological process
GO:0007601	visual perception	IEA	biological process
GO:0007608	sensory perception of smell	IEA	biological process

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Cryptorchidism	MIK: 28606200

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881