• Gene id: 154075

Gene Summary

• Gene Symbol: SAMD3   Gene   UCSC   Ensembl
• Gene name: sterile alpha motif domain containing 3
• Alternate names: sterile alpha motif domain-containing protein 3, SAM domain-containing protein 3,
• Gene location: 6q23.1 (130365867: 130133202)     Exons: 24     NC_000006.12
• OMIM: 0

Protein Summary

• Protein general information: Q8N6K7  
  • Name: Sterile alpha motif domain containing protein 3 (SAM domain containing protein 3)
  • Length: 520  
  • Mass: 61237
• Sequence:

  METWSVEQVCSWLVEKNLGELVHRFQEEEVSGAALLALNDRMVQQLVKKIGHQAVLMDLIKKYKQNTQGLKSPEN
  PKKAALVMQTEAARDYRDEESSSPARHGEQMPSFYPAENLDNGLIDQRVLKQRRNVKQILARSKALQWTKSYVLP
  EFPYDVKCMLAEQKCPDHSMRIRIIEFLQADMTKYLEGSLYPSTQQYNDVVNALLQAHPFLDEDGCGFFLWKRAL
  KDRFKYVRRPIEDDEQVIRNKCKFGHRRGQTRKSLADIRFDEIKLVQIKEEAVCFDSELDEHIKWFQQEYVKTEK
  DWREIDKRMSQTLEIRRKMIGSRTPLKDILKLFPFLKCPYQMFREFQLLTRTDIYKKTRHILESYSENILTSFSV
  VDNPINIVLQEKMKHYTDEDMLKYMKMTATCLLLPDVFGDDPSLFVIMNEQVQVSTPVLEVKNPFNMEVCEFSLY
  LERERLTKVDDCVTALAALVAAFHVFRIECPRRLSQTFNFLETLIFDMHSPYFPSLKEKENEVGFQHPLT

• Structural information:
  • Protein Domains: (4..7-)
    (/note="SAM-)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00184"-)
  • Interpro: IPR001660  IPR013761  IPR042812  IPR042813  
  • Prosite: PS50105
  • CDD: cd09526
  • STRING: ENSP00000402092
• Other Databases: GeneCards:  SAMD3  Malacards:  SAMD3

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)