• Gene id: 153396

Gene Summary

• Gene Symbol: TMEM161B   Gene   UCSC   Ensembl
• Aliases: FLB3342, PRO1313
• Gene name: transmembrane protein 161B
• Alternate names: transmembrane protein 161B,
• Gene location: 5q14.3 (88268905: 88179299)     Exons: 19     NC_000005.10

Protein Summary

• Protein general information: Q8NDZ6  
  • Name: Transmembrane protein 161B
  • Length: 487  
  • Mass: 55482
• Sequence:

  MGVIGIQLVVTMVMASVMQKIIPHYSLARWLLCNGSLRWYQHPTEEELRILAGKQQKGKTKKDRKYNGHIESKPL
  TIPKDIDLHLETKSVTEVDTLALHYFPEYQWLVDFTVAATVVYLVTEVYYNFMKPTQEMNISLVWCLLVLSFAIK
  VLFSLTTHYFKVEDGGERSVCVTFGFFFFVKAMAVLIVTENYLEFGLETGFTNFSDSAMQFLEKQGLESQSPVSK
  LTFKFFLAIFCSFIGAFLTFPGLRLAQMHLDALNLATEKITQTLLHINFLAPLFMVLLWVKPITKDYIMNPPLGK
  ESIPLMTEATFDTLRLWLIILLCALRLAMMRSHLQAYLNLAQKCVDQMKKEAGRISTVELQKMVARVFYYLCVIA
  LQYVAPLVMLLHTTLLLKTLGNHSWGIYPESISTLPVDNSLLSNSVYSELPSAEGKMKVTVTQITVALSSLKNIF
  TPLLFRGLLSFLTWWIAACLFSTSLFGLFYHQYLTVA

• Structural information:
  • Interpro: IPR019395  
  • STRING: ENSP00000426354
• Other Databases: GeneCards:  TMEM161B  Malacards:  TMEM161B

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0016020	membrane	IEA	cellular component
GO:0016021	integral component of membrane	IEA	cellular component
GO:0016020	membrane	IEA	cellular component

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq