• Gene id: 153364

Gene Summary

• Gene Symbol: MBLAC2   Gene   UCSC   Ensembl
• Gene name: metallo-beta-lactamase domain containing 2
• Alternate names: metallo-beta-lactamase domain-containing protein 2,
• Gene location: 5q14.3 (168226003: 168253020)     Exons: 8     NC_000001.11

Protein Summary

• Protein general information: Q68D91  
  • Name: Metallo beta lactamase domain containing protein 2 (EC 3. . . )
  • Length: 279  
  • Mass: 31372
• Sequence:

  MSALEWYAHKSLGDGIFWIQERFYESGNRANIWLVRGSEQDVVIDTGLGLRSLPEYLYSSGLLQDREAKEDAARR
  PLLAVATHVHFDHSGGLYQFDRVAVHHAEAEALARGDNFETVTWLSDSEVVRTPSPGWRARQFRVQAVQPTLILQ
  DGDVINLGDRQLTVMHMPGHSRGSICLHDKDRKILFSGDVVYDGSLIDWLPYSRISDYVGTCERLIELVDRGLVE
  KVLPGHFNTFGAERLFRLASNYISKAGICHKVSTFAMRSLASLALRVTNSRTSP

• Structural information:
  • Interpro: IPR001279  IPR036866  
  • STRING: ENSP00000314776
• Other Databases: GeneCards:  MBLAC2  Malacards:  MBLAC2

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0046872	metal ion binding	IEA	molecular function
GO:0016787	hydrolase activity	IEA	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0003674	molecular_function	ND	molecular function
GO:0070062	extracellular exosome	HDA	cellular component
GO:0008150	biological_process	ND	biological process

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881