• Gene id: 151258

Gene Summary

• Gene Symbol: SLC38A11   Gene   UCSC   Ensembl
• Aliases: AVT2
• Gene name: solute carrier family 38 member 11
• Alternate names: putative sodium-coupled neutral amino acid transporter 11,
• Gene location: 2q24.3 (164955720: 164898198)     Exons: 18     NC_000002.12
• OMIM: 616526

Protein Summary

• Protein general information: Q08AI6  
  • Name: Putative sodium coupled neutral amino acid transporter 11 (Solute carrier family 38 member 11)
  • Length: 406  
  • Mass: 44825
• Sequence:

  MKQAGFPLGILLLFWVSYVTDFSLVLLIKGGALSGTDTYQSLVNKTFGFPGYLLLSVLQFLYPFIAMISYNIIAG
  DTLSKVFQRIPGVDPENVFIGRHFIIGLSTVTFTLPLSLYRNIAKLGKVSLISTGLTTLILGIVMARAISLGPHI
  PKTEDAWVFAKPNAIQAVGVMSFAFICHHNSFLVYSSLEEPTVAKWSRLIHMSIVISVFICIFFATCGYLTFTGF
  TQGDLFENYCRNDDLVTFGRFCYGVTVILTYPMECFVTREVIANVFFGGNLSSVFHIVVTVMVITVATLVSLLID
  CLGIVLELNGVLCATPLIFIIPSACYLKLSEEPRTHSDKIMSCVMLPIGAVVMVFGFVMAITNTQDCTHGQEMFY
  CFPDNFSLTNTSESHVQQTTQLSTLNISIFQ

• Structural information:
  • Interpro: IPR013057  
  • STRING: ENSP00000386272
• Other Databases: GeneCards:  SLC38A11  Malacards:  SLC38A11

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0015171	amino acid transmembrane transporter activity	IBA	molecular function
GO:0003333	amino acid transmembrane transport	IBA	biological process
GO:0006814	sodium ion transport	IEA	biological process
GO:0006865	amino acid transport	IEA	biological process
GO:0016020	membrane	IEA	cellular component
GO:0006811	ion transport	IEA	biological process
GO:0016021	integral component of membrane	IEA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0016020	membrane	IEA	cellular component

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881