• Gene id: 150356

Gene Summary

• Gene Symbol: CHADL   Gene   UCSC   Ensembl
• Aliases: SLRR4B
• Gene name: chondroadherin like
• Alternate names: chondroadherin-like protein,
• Gene location: 22q13.2 (41241770: 41229509)     Exons: 6     NC_000022.11
• OMIM: 606846

Protein Summary

• Protein general information: Q6NUI6  
  • Name: Chondroadherin like protein
  • Length: 762  
  • Mass: 82388
• Sequence:

  MEGPRSSTHVPLVLPLLVLLLLAPARQAAAQRCPQACICDNSRRHVACRYQNLTEVPDAIPELTQRLDLQGNLLK
  VIPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLLLLNLASNHLRELPQEALDGLGSLRRLELEGNALEELR
  PGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGPV
  LSQARGLARLELGHNPLTYAGEEDGLALPGLRELLLDGGALQALGPRAFAHCPRLHTLDLRGNQLDTLPPLQGPG
  QLRRLRLQGNPLWCGCQARPLLEWLARARVRSDGACQGPRRLRGEALDALRPWDLRCPGDAAQEEEELEERAVAG
  PRAPPRGPPRGPGEERAVAPCPRACVCVPESRHSSCEGCGLQAVPRGFPSDTQLLDLRRNHFPSVPRAAFPGLGH
  LVSLHLQHCGIAELEAGALAGLGRLIYLYLSDNQLAGLSAAALEGAPRLGYLYLERNRFLQVPGAALRALPSLFS
  LHLQDNAVDRLAPGDLGRTRALRWVYLSGNRITEVSLGALGPARELEKLHLDRNQLREVPTGALEGLPALLELQL
  SGNPLRALRDGAFQPVGRSLQHLFLNSSGLEQICPGAFSGLGPGLQSLHLQKNQLRALPALPSLSQLELIDLSSN
  PFHCDCQLLPLHRWLTGLNLRVGATCATPPNARGQRVKAAAAVFEDCPGWAARKAKRTPASRPSARRTPIKGRQC
  GADKVGKEKGRL

• Structural information:
  • Protein Domains: (31..6-)
    (/note="LRRNT-1)
    (310..35-)
    (/note="LRRCT-1)
    (387..42-)
    (/note="LRRNT-2)
    (675..72-)
    (/note="LRRCT-2")
  • Interpro: IPR000483  IPR001611  IPR003591  IPR032675  IPR000372  
  • Prosite: PS51450
  • STRING: ENSP00000216241
• Other Databases: GeneCards:  CHADL  Malacards:  CHADL

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0031012	extracellular matrix	IBA	cellular component
GO:0005615	extracellular space	IBA	cellular component
GO:0062023	collagen-containing extracellular matrix	IDA	cellular component
GO:1904027	negative regulation of collagen fibril organization	IDA	biological process
GO:0098633	collagen fibril binding	IDA	molecular function
GO:0005518	collagen binding	IDA	molecular function
GO:0032331	negative regulation of chondrocyte differentiation	ISS	biological process
GO:0005576	extracellular region	IEA	cellular component
GO:0062023	collagen-containing extracellular matrix	IEA	cellular component
GO:0032331	negative regulation of chondrocyte differentiation	IEA	biological process
GO:0030021	extracellular matrix structural constituent conferring compression resistance	ISS	molecular function
GO:0005576	extracellular region	IEA	cellular component

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq