• Gene id: 149986

Gene Summary

• Gene Symbol: LSM14B   Gene   UCSC   Ensembl
• Aliases: C20orf40, FAM61B, FT005, LSM13, RAP55B, bA11M20.3
• Gene name: LSM family member 14B
• Alternate names: protein LSM14 homolog B, LSM14 homolog B, LSM14B, SCD6 homolog B, RNA-associated protein 55B, family with sequence similarity 61, member B, hRAP55B,
• Gene location: 20q13.33 (62122453: 62135377)     Exons: 15     NC_000020.11
• OMIM: 189967

Protein Summary

• Protein general information: Q9BX40  
  • Name: Protein LSM14 homolog B (Protein FAM61B) (RNA associated protein 55B) (hRAP55B)
  • Length: 385  
  • Mass: 42071
• Sequence:

  MSGSSGTPYLGSKISLISKAQIRYEGILYTIDTDNSTVALAKVRSFGTEDRPTDRPAPPREEIYEYIIFRGSDIK
  DITVCEPPKAQHTLPQDPAIVQSSLGSASASPFQPHVPYSPFRGMAPYGPLAASSLLSQQYAASLGLGAGFPSIP
  VGKSPMVEQAVQTGSADNLNAKKLLPGKGTTGTQLNGRQAQPSSKTASDVVQPAAVQAQGQVNDENRRPQRRRSG
  NRRTRNRSRGQNRPTNVKENTIKFEGDFDFESANAQFNREELDKEFKKKLNFKDDKAEKGEEKDLAVVTQSAEAP
  AEEDLLGPNCYYDKSKSFFDNISSELKTSSRRTTWAEERKLNTETFGVSGRFLRGRSSRGGFRGGRGNGTTRRNP
  TSHRAGTGRV

• Structural information:
  • Protein Domains: (241..27-)
    (/note="DFDF-)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00845"-)
  • Interpro: IPR025762  IPR019050  IPR025761  IPR025609  IPR010920   IPR025768  
  • Prosite: PS51512 PS51513 PS51536
  • CDD: cd01736
  • STRING: ENSP00000279068
• Other Databases: GeneCards:  LSM14B  Malacards:  LSM14B

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0003729	mRNA binding	IBA	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0006417	regulation of translation	IEA	biological process
GO:0007275	multicellular organism development	IEA	biological process
GO:0003723	RNA binding	HDA	molecular function

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)