• Gene id: 149954

Gene Summary

• Gene Symbol: BPIFB4   Gene   UCSC   Ensembl
• Aliases: C20orf186, LPLUNC4, RY2G5, dJ726C3.5
• Gene name: BPI fold containing family B member 4
• Alternate names: BPI fold-containing family B member 4, ligand-binding protein RY2G5, likely ortholog of rat probable ligand-binding protein RY2G5, long palate, lung and nasal epithelium carcinoma associated 4, long palate, lung and nasal epithelium carcinoma-associated prote,
• Gene location: 20q11.21 (33081511: 33111750)     Exons: 16     NC_000020.11
• OMIM: 605705

Protein Summary

• Protein general information: P59827  
  • Name: BPI fold containing family B member 4 (Ligand binding protein RY2G5) (Long palate, lung and nasal epithelium carcinoma associated protein 4)
  • Length: 614  
  • Mass: 65055
  • Tissue specificity: Expressed in nasal tissue. {ECO
• Sequence:

  MWMAWCVAALSVVAVCGTSHETNTVLRVTKDVLSNAISGMLQQSDALHSALREVPLGVGDIPYNDFHVRGPPPVY
  TNGKKLDGIYQYGHIETNDNTAQLGGKYRYGEILESEGSIRDLRNSGYRSAENAYGGHRGLGRYRAAPVGRLHRR
  ELQPGEIPPGVATGAVGPGGLLGTGGMLAADGILAGQGGLLGGGGLLGDGGLLGGGGVLGVLGEGGILSTVQGIT
  GLRIVELTLPRVSVRLLPGVGVYLSLYTRVAINGKSLIGFLDIAVEVNITAKVRLTMDRTGYPRLVIERCDTLLG
  GIKVKLLRGLLPNLVDNLVNRVLADVLPDLLCPIVDVVLGLVNDQLGLVDSLIPLGILGSVQYTFSSLPLVTGEF
  LELDLNTLVGEAGGGLIDYPLGWPAVSPKPMPELPPMGDNTKSQLAMSANFLGSVLTLLQKQHALDLDITNGMFE
  ELPPLTTATLGALIPKVFQQYPESCPLIIRIQVLNPPSVMLQKDKALVKVLATAEVMVSQPKDLETTICLIDVDT
  EFLASFSTEGDKLMIDAKLEKTSLNLRTSNVGNFDIGLMEVLVEKIFDLAFMPAMNAVLGSGVPLPKILNIDFSN
  ADIDVLEDLLVLSA

• Structural information:
  • Interpro: IPR017943  IPR001124  IPR017942  
  • STRING: ENSP00000364632
• Other Databases: GeneCards:  BPIFB4  Malacards:  BPIFB4

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0008289	lipid binding	IEA	molecular function
GO:0005576	extracellular region	IEA	cellular component
GO:0005737	cytoplasm	IEA	cellular component
GO:0005576	extracellular region	IEA	cellular component
GO:0005737	cytoplasm	IEA	cellular component

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq