• Gene id: 149499

Gene Summary

• Gene Symbol: LRRC71   Gene   UCSC   Ensembl
• Aliases: C1orf92
• Gene name: leucine rich repeat containing 71
• Alternate names: leucine-rich repeat-containing protein 71, leucine-rich repeat-containing protein C10orf92,
• Gene location: 1q23.1 (156920607: 156941239)     Exons: 10     NC_000001.11

Protein Summary

• Protein general information: Q8N4P6  
  • Name: Leucine rich repeat containing protein 71
  • Length: 559  
  • Mass: 61825
• Sequence:

  MSSEQSAPGASPRAPRPGTQKSSGAVTKKGERAAKEKPATVLPPVGEEEPKSPEEYQCSGVLETDFAELCTRWGY
  TDFPKVVNRPRPHPPFVPSASLSEKATLDDPRLSGSCSLNSLESKYVFFRPTIQVELEQEDSKSVKEIYIRGWKV
  EERILGVFSKCLPPLTQLQAINLWKVGLTDKTLTTFIELLPLCSSTLRKVSLEGNPLPEQSYHKLMALDSTIAHL
  SLRNNNIDDRGAQLLGQALSTLHSCNRTLVSLNLGFNHIGDEGAGYIADGLRLNRSLLWLSLAHNRIQDKGALKL
  AEVLRAFELTHTEVVERRRLLLEKGTQERSRSPSSSRHGDSKTDREKSQMVGISNSALVDKTDKTQTMKTPKGLG
  KKKEKSWELAKKEEKLGSGQSPTQGTPKKEDATKAGKGKVTIPEQKPSRAKGIKIGSREKRSILLESELVVEATE
  VVNPLLEPVEHRDGKVFMPGNKVLLHLNLIRNRITEVGLEGFLATVQYQMQFSKAKSASKGPVGLLWLSLAKNCF
  APQCPAYAIIQELMLPRDPIKAKLREDEAMAFFP

• Structural information:
  • Interpro: IPR001611  IPR032675  
  • STRING: ENSP00000336661
• Other Databases: GeneCards:  LRRC71  Malacards:  LRRC71

Diseases

Associated diseases	References
Non obstructive azoospermia	MIK: 24012201
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
24012201	Non obstructive azoospermia			31 (4 controls, 27 cases)	Male infertility	GSE45885 analyzed by GEO2R (cutoff 1.5 fold)
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)