• Gene id: 148808

Gene Summary

• Gene Symbol: MFSD4A   Gene   UCSC   Ensembl
• Aliases: MFSD4, UNQ3064
• Gene name: major facilitator superfamily domain containing 4A
• Alternate names: major facilitator superfamily domain-containing protein 4A, major facilitator superfamily domain containing 4, major facilitator superfamily domain-containing protein 4,
• Gene location: 1q32.1 (205569013: 205602917)     Exons: 10     NC_000001.11
• OMIM: 610378

Protein Summary

• Protein general information: Q8N468  
  • Name: Major facilitator superfamily domain containing protein 4A (Major facilitator superfamily domain containing protein 4)
  • Length: 514  
  • Mass: 56265
• Sequence:

  MGCDGRVSGLLRRNLQPTLTYWSVFFSFGLCIAFLGPTLLDLRCQTHSSLPQISWVFFSQQLCLLLGSALGGVFK
  RTLAQSLWALFTSSLAISLVFAVIPFCRDVKVLASVMALAGLAMGCIDTVANMQLVRMYQKDSAVFLQVLHFFVG
  FGALLSPLIADPFLSEANCLPANSTANTTSRGHLFHVSRVLGQHHVDAKPWSNQTFPGLTPKDGAGTRVSYAFWI
  MALINLPVPMAVLMLLSKERLLTCCPQRRPLLLSADELALETQPPEKEDASSLPPKFQSHLGHEDLFSCCQRKNL
  RGAPYSFFAIHITGALVLFMTDGLTGAYSAFVYSYAVEKPLSVGHKVAGYLPSLFWGFITLGRLLSIPISSRMKP
  ATMVFINVVGVVVTFLVLLIFSYNVVFLFVGTASLGLFLSSTFPSMLAYTEDSLQYKGCATTVLVTGAGVGEMVL
  QMLVGSIFQAQGSYSFLVCGVIFGCLAFTFYILLLFFHRMHPGLPSVPTQDRSIGMENSECYQR

• Structural information:
  • Interpro: IPR011701  IPR036259  
  • STRING: ENSP00000356115
• Other Databases: GeneCards:  MFSD4A  Malacards:  MFSD4A

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005355	glucose transmembrane transporter activity	IBA	molecular function
GO:0022857	transmembrane transporter activity	IEA	molecular function
GO:0055085	transmembrane transport	IEA	biological process
GO:0016020	membrane	IEA	cellular component
GO:0016021	integral component of membrane	IEA	cellular component
GO:0016020	membrane	IEA	cellular component
GO:1904659	glucose transmembrane transport	IEA	biological process

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq