• Gene id: 147645

Gene Summary

• Gene Symbol: VSIG10L   Gene   UCSC   Ensembl
• Gene name: V-set and immunoglobulin domain containing 10 like
• Alternate names: V-set and immunoglobulin domain-containing protein 10-like, VSIG10-like protein,
• Gene location: 19q13.41 (51342123: 51331535)     Exons: 10     NC_000019.10
• OMIM: 600963

Protein Summary

• Protein general information: Q86VR7  
  • Name: V set and immunoglobulin domain containing protein 10 like (VSIG10 like protein)
  • Length: 867  
  • Mass: 91625
  • Tissue specificity: Expressed in the esophagus, particularly in the suprabasilar layers of the epithelium. Expression is largely reduced in esophageal metaplasia, dysplasia, and adenocarcinoma lesions. {ECO
• Sequence:

  MDNPQALPLFLLLASLVGILTLRASSGLQQTNFSSAFSSDSKSSSQGLGVEVPSIKPPSWKVPDQFLDSKASAGI
  SDSSWFPEALSSNMSGSFWSNVSAEGQDLSPVSPFSETPGSEVFPDISDPQVPAKDPKPSFTVKTPASNISTQVS
  HTKLSVEAPDSKFSPDDMDLKLSAQSPESKFSAETHSAASFPQQVGGPLAVLVGTTIRLPLVPIPNPGPPTSLVV
  WRRGSKVLAAGGLGPGAPLISLDPAHRDHLRFDQARGVLELASAQLDDAGVYTAEVIRAGVSQQTHEFTVGVYEP
  LPQLSVQPKAPETEEGAAELRLRCLGWGPGRGELSWSRDGRALEAAESEGAETPRMRSEGDQLLIVRPVRSDHAR
  YTCRVRSPFGHREAAADVSVFYGPDPPTITVSSDRDAAPARFVTAGSNVTLRCAAASRPPADITWSLADPAEAAV
  PAGSRLLLPAVGPGHAGTYACLAANPRTGRRRRSLLNLTVADLPPGAPQCSVEGGPGDRSLRFRCSWPGGAPAAS
  LQFQGLPEGIRAGPVSSVLLAAVPAHPRLSGVPITCLARHLVATRTCTVTPEAPREVLLHPLVAETRLGEAEVAL
  EASGCPPPSRASWAREGRPLAPGGGSRLRLSQDGRKLHIGNFSLDWDLGNYSVLCSGALGAGGDQITLIGPSISS
  WRLQRARDAAVLTWDVERGALISSFEIQAWPDGPALGRTSTYRDWVSLLILGPQERSAVVPLPPRNPGTWTFRIL
  PILGGQPGTPSQSRVYRAGPTLSHGAIAGIVLGSLLGLALLAVLLLLCICCLCRFRGKTPEKKKHPSTLVPVVTP
  SEKKMHSVTPVEISWPLDLKVPLEDHSSTRAYQAQTPVQLSL

• Structural information:
  • Protein Domains: (302..39-)
    1 (/note="Ig-like-C2-type)
    (402..48-)
    2" (/note="Ig-like-C2-type)
  • Interpro: IPR007110  IPR036179  IPR013783  IPR003599  IPR003598  
  • Prosite: PS50835
  • STRING: ENSP00000335623
• Other Databases: GeneCards:  VSIG10L  Malacards:  VSIG10L

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0016020	membrane	IEA	cellular component
GO:0016021	integral component of membrane	IEA	cellular component
GO:0016020	membrane	IEA	cellular component
GO:0005654	nucleoplasm	IDA	cellular component

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq