|
Gene id |
144406 |
| Gene Summary Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
WDR66 Gene UCSC Ensembl |
|
Aliases |
CFAP251, CaM-IP4, SPGF33 |
|
Gene name |
WD repeat domain 66 |
|
Alternate names |
cilia- and flagella-associated protein 251, WD repeat-containing protein 66, |
|
Gene location |
12q24.31 (121918591: 122003918) Exons: 23 NC_000001.11
|
|
Gene summary(Entrez) |
This protein encoded by this gene belongs to the WD repeat-containing family of proteins, which function in the formation of protein-protein complexes in a variety of biological pathways. This family member appears to function in the determination of mean
|
|
OMIM |
618146 |
|
| Associated diseases |
References |
| Spermatogenesis defects | KEGG: H01282 |
| Multiple morphological anomalies of sperm flagella (MMAF) | MIK: 30122541 |
| Sperm flagellar defects | MIK: 30310178 |
| Cryptorchidism | MIK: 28606200 |
| Male infertility | MIK: 30122540 |
| Multiple morphological abnormalities of the sperm flagellum (MMAF) | MIK: 30122540 |
| Male infertility | MIK: 30310178 |
| Sperm flagellar defects | MIK: 30310178 |
| Teratozoospermia | MIK: 17327269 |
| Unexplained infertility | MIK: 25753583 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 30310178 |
Sperm flag
ellar defe
cts, human
male infe
rtility
|
|
|
|
Male infertility |
|
Show abstract |
| 30122540 |
Multiple m
orphologic
al abnorma
lities of
the sperm
flagellum
(MMAF), Ma
le inferti
lity
|
|
|
78 MMAF-affecte
d subjects
|
Male infertility |
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
13 (5 controls,
8 cases)
|
Male infertility |
GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
19 (6 controls
, 13 cases)
|
Male infertility |
GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 28606200 |
Cryptorchi
dism
|
|
|
Monozgotic twin
s (1 control, I
cwith cryptorc
hidism)
|
Male infertility |
MeDIP-Seq
|
Show abstract |
| 25753583 |
Unexplaine
d infertil
ity
|
|
|
46 (17 fertile
men, 29 male pa
tients)
|
Male infertility |
Microarray
|
Show abstract |
|