• Gene id: 142910

Gene Summary

• Gene Symbol: LIPJ   Gene   UCSC   Ensembl
• Aliases: LIPL1, bA425M17.2
• Gene name: lipase family member J
• Alternate names: lipase member J, lipase J, lipase-like abhydrolase domain-containing protein 1, lipase-like, ab-hydrolase domain containing 1,
• Gene location: 10q23.31 (38620654: 38566259)     Exons: 22     NC_000009.12
• OMIM: 613921

Protein Summary

• Protein general information: Q5W064  
  • Name: Lipase member J (EC 3.1.1. ) (Lipase like abhydrolase domain containing protein 1)
  • Length: 366  
  • Mass: 42388
• Sequence:

  MNISQIISYWGYPDEEYDIVTEDGYILGLYRIPYWRTDNNKNLAQRVVVYLQHGLLTSASSWISNLPNNSLGFIL
  ADAGYDVWMGNSRGNTWSRKHLYLETSSKEFWAFSFDEMAKYDLPASIDFTVKQTRQEEIFYVGHSQGTTIGFIT
  FSTISKIAERIKIFFALAPVFSTKYLKSPLIRMTYKWKSIVMAFSGNKDFLPKTSFKKFIGSKLCPLQIFDKICL
  NILFMMFGYDPKNLNMSRLDVYFSHNPAGTSVQNMLHWSQLLNSTHLKAYDWGSPDLNLVHYNQTTSPLYNMTNM
  NVATAIWNGKSDLLADPEDVNILHSEITNHIYYKTISYYNHIDSLFGLDVYDQVYHEIIDIIQDNL

• Structural information:
  • Interpro: IPR029058  IPR006693  IPR025483  
  • Prosite: PS00120
  • STRING: ENSP00000361007
• Other Databases: GeneCards:  LIPJ  Malacards:  LIPJ

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0043231	intracellular membrane-bounded organelle	IBA	cellular component
GO:0016788	hydrolase activity, acting on ester bonds	IEA	molecular function
GO:0006629	lipid metabolic process	IEA	biological process
GO:0016787	hydrolase activity	IEA	molecular function
GO:0016042	lipid catabolic process	IEA	biological process
GO:0006629	lipid metabolic process	IEA	biological process

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)