|
Gene id |
1394 |
| Gene Summary Protein Summary Gene ontology KEGG pathways Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
CRHR1 Gene UCSC Ensembl |
|
Aliases |
CRF-R, CRF-R-1, CRF-R1, CRF1, CRFR-1, CRFR1, CRH-R-1, CRH-R1, CRHR, CRHR1L |
|
Gene name |
corticotropin releasing hormone receptor 1 |
|
Alternate names |
corticotropin-releasing factor receptor 1, CRH receptor 1, corticotropin-releasing factor type 1 receptor, seven transmembrane helix receptor, |
|
Gene location |
17q21.31 (45784279: 45835827) Exons: 14 NC_000017.11
|
|
Gene summary(Entrez) |
This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal tr
|
|
OMIM |
606847 |
Protein Summary
|
|
| GO accession | Term name | Evidence code | Go category |
|---|
|
|
| Pathway id | Pathway name |
|---|
| hsa04080 | Neuroactive ligand-receptor interaction | | hsa04934 | Cushing syndrome | | hsa04730 | Long-term depression | |
|
| Associated diseases |
References |
| Asthma | PMID:16113459 |
| Asthma | PMID:19663668 |
| Chronic obstructive pulmonary disease | PMID:19210659 |
| obesity | PMID:14724656 |
| Aberrant CpGs in Low Motility Sperm | MIK: 21674046 |
| Unexplained infertility | MIK: 25753583 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 21674046 |
Aberrant C
pGs in Low
Motility
Sperm
|
|
|
18
|
Male infertility |
GSE26881
|
Show abstract |
| 25753583 |
Unexplaine
d infertil
ity
|
|
|
46 (17 fertile
men, 29 male pa
tients)
|
Male infertility |
Microarray
|
Show abstract |
|