• Gene id: 139105

Gene Summary

• Gene Symbol: BEND2   Gene   UCSC   Ensembl
• Aliases: CXorf20
• Gene name: BEN domain containing 2
• Alternate names: BEN domain-containing protein 2,
• Gene location: Xp22.13 (18220903: 18162930)     Exons: 14     NC_000023.11
• Gene summary(Entrez): This gene encodes a protein which has two BEN domains in the C-terminus. These domains are found in proteins which participate in protein and DNA interactions which occur during chromatin restructuring or transcription. Alternative splicing results in mul
• OMIM: 605183

Protein Summary

• Protein general information: Q8NDZ0  
  • Name: BEN domain containing protein 2
  • Length: 799  
  • Mass: 87919
• Sequence:

  MSERTQEQDFVIITVDDSDDNNDCSIEMVEVSETADNSTNDIADDSTYVTADNPTDDTATQPNFPGGNDGHHRPL
  QMSYGSGSVTQAGVQWHDHSSLQPQPLGLKQFFHLSLPSSWDDRRTPPCPVAHGDQIVSQINHPVHLRRYSYNSE
  EVDFPKRGRFYTPEVQSSISPPAERQETHAWASPAVTSLESAACHELQEADLSESLSYPRIVSSSSLQQYVAQGG
  SFPCFGMPWNFISGGAESTNAVISFANATTAVPMAVLSRRESSLANNPGVVNYSALPENENVGPGRALSSFCFHP
  NLEMPERPANSSKNSTETANYPTLMGNYNGQNTASLSVFIPPYFAEKIILTEMPGTTETNVENNSQTVYYPALSG
  NTSAPYPASSYLPITSNFESGPQMSYGTMSYSTEMKNNCDQDDASASACLTPDFALLPLNILVKVDTNTENSVNT
  MNRSTLLDSDSGQDSSSSSVCIPPKYGYLGDPKRNVRVLKIHLLAVQNMAKPKQAACYLVRILFSKEILISSSVD
  IHLKDSQSLDPNKMAALREYLATTFPTCDLHEHGKDWQDCISGINSMIYCLCSEGKSTPKTVRKNKKRTNRVASA
  SADRNDQRGRDGGEGCSWMFQPMNNSKMREKRNLQPNSNAIPEGMREPSTDNPEEPGEAWSYFGRPWRNIRMPCS
  VLTLAKTKSCASLSARYLIQKLFTKDVLVQSNVYGNLKHGLCALDPNKISALREFLQENYPICDLSENGRDWKSC
  VTSINSGIRSLRHDVRRAEARSQSLPAVTPPELEQESKPGDPDATDPST

• Structural information:
  • Protein Domains: (483..58-)
    (/note="BEN-1)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00784-)
    (667..76-)
    (/note="BEN-2)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00784"-)
  • Interpro: IPR018379  IPR042810  
  • Prosite: PS51457
  • STRING: ENSP00000369372
• Other Databases: GeneCards:  BEND2  Malacards:  BEND2

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881