|
Gene id |
137964 |
| Gene Summary KEGG pathways Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
GPAT4 Gene UCSC Ensembl |
|
Aliases |
1-AGPAT 6, AGPAT6, LPAAT-zeta, LPAATZ, TSARG7 |
|
Gene name |
glycerol-3-phosphate acyltransferase 4 |
|
Alternate names |
glycerol-3-phosphate acyltransferase 4, 1-AGP acyltransferase 6, 1-acyl-sn-glycerol-3-phosphate acyltransferase zeta, 1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase, zeta), glycerol-3-phosphate acyltransferase 6, lysophos, |
|
Gene location |
8p11.21 (41578189: 41625000) Exons: 16 NC_000010.11
|
|
Gene summary(Entrez) |
Lysophosphatidic acid acyltransferases (EC 2.3.1.51) catalyze the conversion of lysophosphatidic acid (LPA) to phosphatidic acid (PA). LPA and PA are involved in signal transduction and lipid biosynthesis.[supplied by OMIM, Apr 2004]
|
|
OMIM |
608143 |
|
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| Associated diseases |
References |
| Plays a crucial role in speramtogenesis | MIK: 19657568 |
| Plays a crucial role in speramtogenesis | MIK: 16625827 |
| Aberrant CpGs in Low Motility Sperm | MIK: 21674046 |
| Cryptorchidism | MIK: 28606200 |
| Plays an important role in spermatogenesis and sexual maturation | MIK: 16625827 |
| Plays an important role in spermatogenesis, especially in mid-meiosis | MIK: 19657568 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 19657568 |
Plays an i
mportant r
ole in spe
rmatogenes
is, especi
ally in mi
d-meiosis
|
|
|
|
Male infertility |
|
Show abstract |
| 16625827 |
Plays an i
mportant r
ole in spe
rmatogenes
is and sex
ual matura
tion
|
|
|
|
Male infertility |
|
Show abstract |
| 21674046 |
Aberrant C
pGs in Low
Motility
Sperm
|
|
|
18
|
Male infertility |
GSE26881
|
Show abstract |
| 28606200 |
Cryptorchi
dism
|
|
|
Monozgotic twin
s (1 control, I
cwith cryptorc
hidism)
|
Male infertility |
MeDIP-Seq
|
Show abstract |
|