• Gene id: 130814

Gene Summary

• Gene Symbol: SLC66A3   Gene   UCSC   Ensembl
• Aliases: C2orf22, PQLC3
• Gene name: solute carrier family 66 member 3
• Alternate names: solute carrier family 66 member 3, PQ loop repeat containing 3, PQ-loop repeat-containing protein 3,
• Gene location: 2p25.1 (39459023: 39479505)     Exons: 11     NC_000004.12

Protein Summary

• Protein general information: Q8N755  
  • Name: Solute carrier family 66 member 3 (PQ loop repeat containing protein 3)
  • Length: 202  
  • Mass: 22575
• Sequence:

  MEAALLGLCNWSTLGVCAALKLPQISAVLAARSARGLSLPSLLLELAGFLVFLRYQCYYGYPPLTYLEYPILIAQ
  DVILLLCIFHFNGNVKQATPYIAVLVSSWFILALQKWIIDLAMNLCTFISAASKFAQLQCLWKTRDSGTVSALTW
  SLSSYTCATRIITTLMTTNDFTILLRFVIMLALNIWVTVTVLRYRKTAIKAE

• Structural information:
  • Interpro: IPR016817  IPR006603  
  • STRING: ENSP00000295083
• Other Databases: GeneCards:  SLC66A3  Malacards:  SLC66A3

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0016021	integral component of membrane	IEA	cellular component
GO:0016020	membrane	IEA	cellular component
GO:0016020	membrane	IEA	cellular component

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881