• Gene id: 126668

Gene Summary

• Gene Symbol: TDRD10   Gene   UCSC   Ensembl
• Gene name: tudor domain containing 10
• Alternate names: tudor domain-containing protein 10,
• Gene location: 1q21.3 (154502218: 154548146)     Exons: 20     NC_000001.11
• OMIM: 0

Protein Summary

• Protein general information: Q5VZ19  
  • Name: Tudor domain containing protein 10
  • Length: 366  
  • Mass: 40941
• Sequence:

  MSWNISHPQLSDKLFGKNGVLEEQKSPGFKKRETEVYVGNLPLDISKEEILYLLKDFNPLDVHKIQNGCKCFAFV
  DLGSMQKVTLAIQELNGKLFHKRKLFVNTSKRPPKRTPDMIQQPRAPLVLEKASGEGFGKTAAIIQLAPKAPVDL
  CETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSVRGEAGLLVTSIVPKTPFFWAMHVTEALHQNMQA
  LFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDS
  DDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSAVTAPASNLAVVPPLLPLGCLQQAAA

• Structural information:
  • Protein Domains: (34..10-)
    (/note="RRM-)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00176-)
    (210..31-)
    (/note="Tudor"-)
  • Interpro: IPR012677  IPR035979  IPR000504  IPR002999  
  • Prosite: PS50102
  • STRING: ENSP00000357465
• Other Databases: GeneCards:  TDRD10  Malacards:  TDRD10

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0003676	nucleic acid binding	IEA	molecular function
GO:0003723	RNA binding	IEA	molecular function

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200
Sertoli cell only syndrome	MIK: 23869807
Non obstructive azoospermia	MIK: 23869807
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
23869807	Non obstructive azoospermia, Sertoli cell only syndrome			20 (4 controls, 16 cases)	Male infertility	GSE45887 analyzed by GEO2R (cutoff 1.5 fold)
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq